Efficacy and Safety of Edoxaban in Patients With Atrial Fibrillation and Mitral Stenosis

Summary

This study aims to compare the efficacy and safety of the edoxaban and the warfarin in atrial fibrillation patients with mitral stenosis. The study design is a multicenter, randomized, open-label, investigator initiated phase 2 trial. The patients were randomly assigned to Edoxaban or Warfarin groups. Primary outcome was a composite of stroke and systemic arterial thromboembolism. The safety outcome was major bleeding.

Timeline

Start

2022-05-20

Primary completion

2024-05-20

Completion

2026-05-20

Drugs

Indications