drugset / Trial / NCT05556356

Effect of Perioperative Acetaminophen Dosing on Patients Undergoing Surgical Treatment of Basilar Thumb Arthritis

NCT05556356 ↗

Phase 4 Terminated 23 enrolled Indiana Hand to Shoulder Center
RandomizedParallel-groupDouble-blindOther

Summary

Basilar thumb arthritis is a common problem that affects 7% of men and 15% of women. It is regarded as one of the more painful procedures commonly performed by hand surgeons. Opioid overuse and diversion are significant problems in the country that contribute to opioid addiction as well as deaths from opioid overdose. Prior studies have examined the effect of different nerve block compositions on perioperative and postoperative analgesia, but none have looked at perioperative loading analgesia. We will attempt to address this problem by exploring alternative analgesia regimens to decrease opioid prescribing after 1st carpometacarpal (CMC) joint arthroplasty.

Timeline

Start
2022-09-13
Primary completion
2024-05-06
Completion
2024-05-06

Outcome

Outcome not reported

Stopped: “Physician decision”

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetaminophen Small molecule 1000 mg —

Indications