drugset / Trial / NCT05556408

High-Resolution Solid-State Manometry of the Effect of Succinylcholine on Barrier Pressure

NCT05556408

Phase 4 Completed 14 enrolled China-Japan Friendship Hospital
NaSingle-groupOpen-labelPrevention

Summary

The lower esophageal sphincter(LES)plays a key role in preventing regurgitation and aspiration. The pressure of LES partly comes from striated muscles derived from the crural portion of the diaphragm. The effect of succinylcholine on esophagogastric junction during anesthesia induction is not clear. We conducted a prospective interventional study on the effect of succinylcholine on the barrier pressure (BrP) of the esophagogastric junction.

Timeline

Start
2015-03-01
Primary completion
2015-12-30
Completion
2015-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Suxamethonium Other / unclassified 1.5 mg/kg Intravenous

Indications

No indication recorded.