Drugs / Suxamethonium
Suxamethonium
also known as
Succinylcholine · Anectine · CELOCURINE · Chlorure de suxamethonium · Choline chloride succinate (2:1) · Cloruro de suxametonio · NSC-151059 · NSC-49132 · +17 more
Regulatory milestones approvals, filings & regulatory actions · 1 recorded
| Milestone | Jurisdiction | Brand | Indication | Date | Sentence it was read from |
|---|---|---|---|---|---|
| Approved | US (FDA) | ANECTINE | — | 1952-08-20 | fda.gov ↗ |
Trials 10
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| Phase | Registry id | Dates | Indication | Sponsor | Status | Outcome |
|---|---|---|---|---|---|---|
| Phase 21 trial | ||||||
| Phase 2 | NCT03532178 | Jan 2019 → Mar 2022 | — | University of California, San Francisco | Completed | No outcome recorded |
| Phase 46 trials · 1 met primary · 1 missed | ||||||
| Phase 4 | NCT05658692 | Oct 2022 → Oct 2023 | acute respiratory distress syndrome | Second Affiliated Hospital, School of Medicine, Zhejiang University | Unknown | No outcome recorded |
| Phase 4 | NCT02635542 | Mar 2016 → Sep 2017 | — | University of Chicago | Completed | Missed primary |
| Phase 4 | NCT02425449 | Apr 2015 → Jan 2017 | — | University of Toledo Health Science Campus | Completed | No outcome recorded |
| Phase 4 | NCT05556408 | Mar → Dec 2015 | — | China-Japan Friendship Hospital | Completed | No outcome recorded |
| Phase 4 | NCT02237443 | Aug → Nov 2014 | — | University of Washington | Completed | Met primary |
| Phase 4 | NCT01718236 | Sep 2012 → Jan 2015 | pregnancy disorder | Brno University Hospital | Completed | No outcome recorded |
| Phase not applicable3 trials | ||||||
| — | NCT03469323 | Mar 2018 → Jul 2019 | lung neoplasm | National Taiwan University Hospital | Unknown | No outcome recorded |
| — | NCT01441960 | May 2011 → Jul 2013 | — | Massachusetts General Hospital | Completed | No outcome recorded |
| — | NCT00986583 | Sep 2009 → Jul 2010 | — | The Cleveland Clinic | Completed | No outcome recorded |
| Comparator or background therapy32 trials | ||||||
| Phase 0 | NCT07247968 Background | Nov 2025 → Nov 2026 expected | depressive disorder | Min Su | Recruiting | No outcome recorded |
| Phase 2 | NCT03448068 Background | Apr 2018 → Jan 2020 | — | Mayo Clinic | Completed | Met primary |
| Phase 2 | NCT02676011 Comparator | Feb → May 2016 | — | Assiut University | Completed | No outcome recorded |
| Phase 2 | NCT01571908 Comparator | Sep 2012 → Jul 2015 | — | University Hospital, Geneva | Completed | Missed primary |
| Phase 2/3 | NCT03367988 Background | Dec 2018 → Jan 2023 | drug dependence | University of South Florida | Unknown | No outcome recorded |
| Phase 3 | NCT06271174 Background | Jun 2024 → Jun 2026 | — | Nantes University Hospital | Unknown | No outcome recorded |
| Phase 3 | NCT04581395 Comparator | Oct 2020 → Apr 2023 | — | Indiana University | Completed | No outcome recorded |
| Phase 3 | NCT04709315 Comparator | Oct 2020 → Jan 2021 | — | South Valley University | Unknown | No outcome recorded |
| Phase 3 | NCT03960801 Comparator | Oct 2019 → Apr 2021 | — | Nantes University Hospital | Completed | Missed primary |
| Phase 3 | NCT02822144 Background | Sep 2016 → Aug 2020 | stroke disorder | Rennes University Hospital | Completed | No outcome recorded |
| Phase 3 | NCT02000674 Comparator | Dec 2013 → Jul 2016 | — | Centre Hospitalier Universitaire de la Réunion | Completed | Missed primary |
| Phase 3 | NCT00751179 Comparator | Nov 2008 → Dec 2009 | — | Merck Sharp & Dohme LLC | Completed | No outcome recorded |
| Phase 3 | NCT00474253 Comparator | Feb → Aug 2006 | — | Merck Sharp & Dohme LLC | Completed | Met primary |
| Phase 4 | NCT07835295 Comparator | Sep 2026 → Sep 2028 expected | — | Mayo Clinic | Not yet recruiting | No outcome recorded |
| Phase 4 | NCT06772727 Comparator | Feb → Oct 2025 | hypotensive disorder | Cairo University | Completed | No outcome recorded |
| Phase 4 | NCT06029049 Comparator | Sep 2023 → Jun 2025 overdue | — | The University of Texas Health Science Center, Houston | Recruiting | No outcome recorded |
| Phase 4 | NCT04868409 Comparator | Aug 2021 → Mar 2024 | — | Matias Vested | Completed | No outcome recorded |
| Phase 4 | NCT03263117 Comparator | Jul 2018 → Apr 2023 | stroke disorder | The University of Texas Health Science Center, Houston | Completed | No outcome recorded |
| Phase 4 | NCT02410590 Comparator | Jul 2015 → Oct 2016 | — | Merck Sharp & Dohme LLC | Withdrawn | No outcome recorded |
| Phase 4 | NCT01941628 Comparator | Aug 2014 → Dec 2016 | — | Charles University, Czech Republic | Completed | No outcome recorded |
| Phase 4 | NCT01579864 Comparator | Jan 2012 → Jun 2015 | — | Hopital Foch | Terminated | No outcome recorded |
| Phase 4 | NCT00953550 Comparator | Sep 2009 → Jan 2011 | — | Rigshospitalet, Denmark | Completed | No outcome recorded |
| Phase 4 | NCT01474252 Background | Jul 2008 → Dec 2012 | — | Siriraj Hospital | Completed | No outcome recorded |
| Phase 4 | NCT01907217 Background | May 2008 → Nov 2013 | depressive disorder | St Patrick's Hospital, Ireland | Completed | No outcome recorded |
| Phase 4 | NCT00355368 Comparator | Aug 2006 | — | University Hospital, Basel, Switzerland | Completed | No outcome recorded |
| Phase 4 | NCT00815048 Comparator | Jan 2006 → Feb 2008 | — | King Saud University | Completed | No outcome recorded |
| — | NCT06709066 Comparator | Nov 2024 → Dec 2025 overdue | — | Peng Liang | Not yet recruiting | No outcome recorded |
| — | NCT01996358 Comparator | Aug 2015 → Dec 2017 | — | Dr. Horst Schmidt Klinik GmbH | Suspended | No outcome recorded |
| — | NCT01966484 Comparator | Oct 2013 → Jul 2014 | — | Dr. Horst Schmidt Klinik GmbH | Completed | No outcome recorded |
| — | NCT01902641 Comparator | Oct 2011 → Mar 2012 | pharyngitis | Dr. Horst Schmidt Klinik GmbH | Completed | No outcome recorded |
| — | NCT02667353 Background | Jun 2011 → Jun 2014 | depressive disorder | Universitaire Ziekenhuizen KU Leuven | Completed | No outcome recorded |
| — | NCT00462644 Comparator | Feb → Aug 2006 | adrenocortical insufficiency | University of Tennessee | Completed | No outcome recorded |
Press releases naming this drug 2 releases
| Date | Issuer | Release |
|---|---|---|
| 2022-03-30 | Meitheal Pharmaceuticals, Inc. | Succinylcholine Chloride Injection, USP Now Available meithealpharma.com ↗ |
| 2020-06-09 | Amphastar Pharmaceuticals, Inc. | Amphastar Pharmaceuticals, Inc. Receives FDA Approval for Succinylcholine Chloride Injection USP, 200 mg/10 mL (20 mg/mL) Multiple-Dose Vial amphastar.com ↗ |
Evidence & citations 28 cited values
Every value below carries the sentence it was read from. 43 sources stand behind the page.
| Field | Value | Cited text |
|---|---|---|
| Known as | Suxamethonium | “Rocuronium: Zemuron. Sugammadex: Bridion. Succinylcholine: Suxamethonium” NCT03532178 ↗4“A rapid-acting intravenous curare Suxamethonium 1 mg/kg” NCT06271174 ↗ |
| Known as | Anectine | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | CELOCURINE | “Nowadays the use of Succinylcholine (CELOCURINE), a neuromuscular blockade with a short duration of action, is recommended in this indication.” NCT03960801 ↗ |
| Known as | Chlorure de suxamethonium | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Choline chloride succinate (2:1) | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Cloruro de suxametonio | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | NSC-151059 | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | NSC-49132 | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Quelicin | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Quelicin (succinylcholine chloride injection United States Pharmacopeia [USP]) | “Quelicin® (succinylcholine chloride injection United States Pharmacopeia [USP])” NCT00751179 ↗ |
| Known as | Quelicin preservative free | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Scoline | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Succinylcholine | “1. experimental group The patients were given intravenous injection of 0.25 mg / kg esketamine, 1.5 mg / kg propofol and 1 mg / kg succinylcholine in turn.” NCT07247968 ↗38“Nowadays the use of Succinylcholine (CELOCURINE), a neuromuscular blockade with a short duration of action, is recommended in this indication.” NCT03960801 ↗ “muscle paralysis may be achieved with succinylcholine or non-depolarizing paralytic (rocuronium or vecuronium)” NCT03263117 ↗ “Anesthesia will be induced with rocuronium 1mg, propofol 3-6 mg/kg, and succinylcholine 1.5 mg/kg” NCT03367988 ↗ “neuromuscular block w/succinylcholine and/or rocuronium” NCT03448068 ↗ “Succinylcholine 1-1.5mg/kg” NCT01474252 ↗ “Succinylcholine” NCT05658692 ↗ |
| Known as | Succinylcholine bromide | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Succinylcholine cation | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | SUCCINYLCHOLINE CHLORIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Succinylcholine ion | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Sucostrin | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Suxamethone | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Suxamethonii chloridum | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | SUXAMETHONIUM BROMIDE | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Suxamethonium cation | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Suxamethonium chloride | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Suxamethonium chloride dihydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Suxamethonium chloride hydrate | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Known as | Suxamethonium ion | ChEMBL registry synonym — accepted as the source's own label CHEMBL703 ↗ |
| Modality | Other / unclassified | “two commonly used neuromuscular blocking agents (succinylcholine and rocuronium)” NCT01441960 ↗ |
| Route | Intravenous | “1mg/kg iv” NCT00355368 ↗ |