drugset
drugset / Trial / NCT06029049

Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine

NCT06029049 ↗

Phase 4 Recruiting 152 enrolled The University of Texas Health Science Center, Houston
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to assess and compare conditions for tracheal intubation obtained with modified time principal induction with 0.6 mg/kg rocuronium and 1 mg/kg succinylcholine. Specifically, the investigators will be evaluating ease of laryngoscopy, vocal cord view, vocal cord opening, and movement of limbs and coughing during tracheal intubation in order to assess intubation conditions, to compare efficiency and success rate of tracheal intubation between two induction agents and to determine the rate of patient awareness during induction and post-operative recall of paralysis.

Timeline

Start
2023-09-13
Primary completion
2025-06-01
Completion
2025-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Rocuronium Other / unclassified 0.6 mg/kg Intravenous
Comparator Suxamethonium Other / unclassified 1 mg/kg Intravenous
Background Fentanyl Other / unclassified 1 ug/kg Intravenous
Background Fentanyl Other / unclassified 2 ug/kg Intravenous
Background Lidocaine Other / unclassified 1 mg/kg Intravenous
Background Propofol Small molecule 1 mg/kg Intravenous
Background Propofol Small molecule 2 mg/kg Intravenous

Indications

No indication recorded.