Avoid With Locoregional Analgesia Persistant Postoperative Pain In Children
Summary
Persistent postoperative pain is a substantial pain (scores 4-10 using a 0-10 numeric scale) that develops 3 months after surgery. Persistent postoperative pain can be a problem even in ambulatory surgery. Loco-regional analgesia could prevent the occurrence of this pathology but contradictory results are found in ancient studies. This study is the first randomized controlled study in children about loco-regional analgesia and persistent postoperative pain in traumatologic orthopedic surgery. One interventional arm will receive a locoregional analgesia after general anesthesia and before incision. The other arm will only receive systemic analgesia during general anesthesia. The incidence of persistent postoperative pain at 3, 6 and 12 months will be compared in these two groups. The goal is to show the decrease of the incidence of the persistent postoperative pain in the group "locoregional analgesia".
Timeline
- Start
- 2024-06-06
- Primary completion
- 2026-06
- Completion
- 2026-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mepivacaine | Other / unclassified | — | Other |
| Background | Propofol | Small molecule | 2 mg/kg | Intravenous |
| Background | Propofol | Small molecule | 5 mg/kg | Intravenous |
| Background | Sevoflurane | Other / unclassified | — | Inhaled |
| Background | Suxamethonium | Other / unclassified | 1 mg/kg | Intravenous |
Indications
No indication recorded.