drugset / Trial / NCT01718236
Modern Myorelaxation Procedure and Reversal of Neuromuscular Blockade With General Anesthesia for Caesarean Section
Phase 4
Completed
500 enrolled
Brno University Hospital
IGA - internal grant agency, Ministry of Health · collabSt. Anne's University Hospital Brno, Czech Republic · collabUniversity Hospital Olomouc · collab
RandomizedFactorialSingle-blindTreatment
Summary
The project aims to introduce into clinical practice for Caesarean section conducted under general anesthesia with the rapid induction myorelaxation with rocuronium and the reversal of neuromuscular blockade by using sugammadex. The aim is to demonstrate at least the same efficiency and confirm the safety of the procedure for both mother and newborn compared with older procedure.
Timeline
- Start
- 2012-09
- Primary completion
- 2015-01
- Completion
- 2015-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Neostigmine | Other / unclassified | 0.03 mg/kg | — |
| Subject | Rocuronium | Other / unclassified | 0.3 mg/kg | — |
| Subject | Rocuronium | Other / unclassified | 1 mg/kg | — |
| Subject | Sugammadex | Other / unclassified | 2 mg/kg | — |
| Subject | Sugammadex | Other / unclassified | 4 mg/kg | — |
| Subject | Sugammadex | Other / unclassified | 16 mg/kg | — |
| Subject | Suxamethonium | Other / unclassified | 1 mg/kg | — |
| Background | Atropine | Other / unclassified | 0.01 mg/kg | — |