Succinylcholine vs Rocuronium for Prehospital Emergency Intubation

NCT02000674 ↗

Phase 3 Completed 1321 enrolled Centre Hospitalier Universitaire de la Réunion Hôpital Necker-Enfants Malades · collab Unité de Soutien Méthodologique (CHU de La Réunion) · collab

RandomizedParallel-groupSingle-blindTreatment

Summary

All adult patients with spontaneous cardiac activity and requiring tracheal intubation in the pre hospital emergency context will be included in order to compare the use of succinylcholine vs Rocuronium for prehospital emergency intubation.

Timeline

Start: 2013-12
Primary completion: 2016-07
Completion: 2016-07

Publications

Guihard B, Chollet-Xemard C, Lakhnati P, Vivien B, Broche C, Savary D, Ricard-Hibon A, Marianne Dit Cassou PJ, Adnet F, Wiel E, Deutsch J, Tissier C, Loeb T, Bounes V, Rousseau E, Jabre P, Huiart L, Ferdynus C, Combes X. Effect of Rocuronium vs Succinylcholine on Endotracheal Intubation Success Rate Among Patients Undergoing Out-of-Hospital Rapid Sequence Intubation: A Randomized Clinical Trial. JAMA. 2019 Dec 17;322(23):2303-2312. doi: 10.1001/jama.2019.18254.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Rocuronium	Other / unclassified	1.2 mg/kg	Intravenous
Comparator	Suxamethonium	Other / unclassified	1 mg/kg	Intravenous

Indications

No indication recorded.