drugset / Trial / NCT06772727
Lidocaine-based Versus Opioid-based Induction of Anesthesia in Emergency Laparotomy
RandomizedParallel-groupTriple-blindOther
Summary
Lidocaine-based anesthesia had been recently reported as a successful regimen for induction of anesthesia in elderly population with better hemodynamic profile than opioid-based induction. The investigators hypothesize that lidocaine-based induction of anesthesia would provide superior hemodynamic profile compared to conventional opioid-based induction of anesthesia in emergency laparotomy.
Timeline
- Start
- 2025-02-01
- Primary completion
- 2025-10-30
- Completion
- 2025-10-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Fentanyl | Other / unclassified | 1 ug/kg | Intravenous |
| Comparator | Lidocaine | Other / unclassified | 1 mg/kg | Intravenous |
| Comparator | Propofol | Small molecule | 2 mg/kg | Intravenous |
| Comparator | Suxamethonium | Other / unclassified | 1 mg/kg | — |