drugset / Trial / NCT05569993

Glutamine and Traumatic Brain Injury

NCT05569993

Phase 0 Unknown 60 enrolled Assiut University
RandomizedParallel-groupTriple-blindTreatment

Summary

Glutamate is an important neurotransmitter present in over 90% of all brain synapses and is a naturally occurring molecule that nerve cells use to send signals to other cells in the central nervous system. Glutamate is a non-essential amino acid with restricted passage to the brain from the blood. In the CNS, glutamate is synthesised in neurons as part of the glutamate-glutamine cycle.5,6 so it plays an essential role in normal brain functioning and can improve situations related to impaired cognitive,motor and emotional functions and can be used to improve traumatic brain injury patient general health status

Timeline

Start
2022-10-30
Primary completion
2023-10-30
Completion
2023-12-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Glutamine Other / unclassified 0.3 mg/kg