drugset / Trial / NCT05573581

Effect of Botox Injection in Anterior Belly of Digastric on Skeletal Relapse Following Mandibular Advancement Surgery

NCT05573581 ↗

Phase 3 Unknown 10 enrolled Cairo University
RandomizedParallel-groupDouble-blindPrevention

Summary

The purpose of this study is to test whether Botox injection in anterior belly of digastric muscle in BSSO for mandibular advancement surgery could reduce the tendency of postoperative relapse. Research question: (P) In patient has skeletal class II mandibular retrognathism, (I) will Botox injection in anterior belly of digastric. (O) Affect the relapse of the mandible after mandibular advancement orthognathic surgery? Participants will be undergo Botox injection in anterior belly of digastric and bilateral sagittal split surgery

Timeline

Start
2023-01
Primary completion
2025-01
Completion
2025-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Botulinum toxin type A Protein / enzyme biologic 20 iu Intramuscular

Indications