drugset / Trial / NCT05575505

Phosphodiesterase Inhibitors, Pentoxifylline, as Adjunctive Therapy in Patients With Ulcerative Colitis.

NCT05575505

Phase 2 Recruiting 44 enrolled Tanta University
RandomizedParallel-groupDouble-blindTreatment

Summary

Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disease characterized by diffused inflammation of the colon and rectum mucosa; however, the exact underlying mechanisms of UC remain poorly understood. Also, it is associated with high risk of colon cancer, so there is a continuous need for introducing new therapies that decrease progression, and hence better outcomes

Timeline

Start
2023-02-02
Primary completion
2026-02
Completion
2026-02

Drugs

EvaluationDrugModalityDoseRoute
Comparator Pentoxifylline Small molecule 400 mg