drugset / Trial / NCT05577923

Exploring Whether Disease-free Intervals Can Guide Endocrine Combined Targeted Therapy for ER+/HER2+ Advanced Breast Cancer (T-sunflower)

NCT05577923

Phase 2 Unknown 126 enrolled Fudan University
NaSingle-groupOpen-labelTreatment

Summary

This study is a prospective, single-arm, phase II clinical study for patients with ER+/HER2+ advanced breast cancer.

Timeline

Start
2022-11-01
Primary completion
2024-09-01
Completion
2026-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Dalpiciclib Small molecule 125 mg Oral
Subject Fulvestrant Small molecule 500 mg Intramuscular
Subject Pyrotinib Small molecule 320 mg Oral
Subject Trastuzumab Monoclonal antibody 6 mg/kg Intravenous

Indications