drugset / Trial / NCT05581901
Perioperative Methadone in Hip Fracture Patients
Non-randomizedSequentialDouble-blindTreatment
Summary
Postoperative analgesic treatment needs to be improved. Numerous studies suggest that a single dose of Methadone given during surgery significantly ameliorates postoperative pain and reduces postoperative opioid consumption. Perioperative methadone is already used in isolated cases such as patients with chronic pain or patients with high morphine tolerance. However, it is not routinely used in the elderly and fragile, and there is insufficient reliable evidence on this treatment and population. Further investigation is highly relevant and necessary.
Timeline
- Start
- 2023-01-12
- Primary completion
- 2023-03-23
- Completion
- 2023-04-04
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methadone | Other / unclassified | 0.1 mg/kg | Intravenous |
| Subject | Methadone | Other / unclassified | 0.15 mg/kg | Intravenous |
| Subject | Methadone | Other / unclassified | 0.2 mg/kg | Intravenous |
Indications
No indication recorded.