drugset / Trial / NCT05582317
Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Objective: This study was conducted to evaluate the efficacy of combination of biodentine with simvastatin as a pulpotomy agent for vital primary molars clinically and radiographically. Study design: 60 primary molars in 20 children aged 4-7 years old were randomly allocated to three groups, Biodentine, Simvastatin and combination of Biodentine and simvastatin. Clinical and radiographic examinations were conducted at 1, 3, 6, 9 and 12 months after treatment. Key words: Pulpotomy, Primary teeth, Biodentine, Simvastatin.
Timeline
- Start
- 2021-05-23
- Primary completion
- 2022-05-24
- Completion
- 2022-07-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Biodentine | Other / unclassified | — | Other |
| Comparator | Simvastatin | Small molecule | 1.5 mg | Other |