drugset / Trial / NCT05582317

Efficacy of Combination of Biodentine and Simvastatin as a Pulp Capping Materials in Vital Pulpotomy of Primary Molars

NCT05582317

Completed 20 enrolled Suez Canal University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Objective: This study was conducted to evaluate the efficacy of combination of biodentine with simvastatin as a pulpotomy agent for vital primary molars clinically and radiographically. Study design: 60 primary molars in 20 children aged 4-7 years old were randomly allocated to three groups, Biodentine, Simvastatin and combination of Biodentine and simvastatin. Clinical and radiographic examinations were conducted at 1, 3, 6, 9 and 12 months after treatment. Key words: Pulpotomy, Primary teeth, Biodentine, Simvastatin.

Timeline

Start
2021-05-23
Primary completion
2022-05-24
Completion
2022-07-25

Drugs

EvaluationDrugModalityDoseRoute
Comparator Biodentine Other / unclassified Other
Comparator Simvastatin Small molecule 1.5 mg Other

Indications