drugset / Trial / NCT05584228
Medical Treatment Versus Surgery in Stricturing Small Bowel Crohn's Disease
Not yet recruiting
150 enrolled
Nantes University Hospital
Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The objective of the SMART trial is to compare a combination therapy using azathioprine and subcutaneous infliximab versus ileocecal resection in patients with symptomatic small bowel Crohn's disease.
Timeline
- Start
- 2026-10-01
- Primary completion
- 2030-04-01
- Completion
- 2031-04-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Azathioprine | Small molecule | 2 mg/kg | Oral |
| Subject | Azathioprine | Small molecule | 2.5 mg/kg | Oral |
| Subject | Infliximab | Monoclonal antibody | — | Subcutaneous |