drugset / Trial / NCT05586009
Comparative Study of Different Doses of Magnesium as a Protective Agent in Nephrotoxicity in Cancer Patients
RandomizedParallel-groupSingle-blindPrevention
Summary
The goal of this \[ type of study: intervential study is to compare between different doses of magnesium to prevent cisplatin induced nephrotoxicity.\] In 75 participant population with head and neck cancer recieved cisplatin it aims to answer are: • • optimal doses of magnesium as 3 groups each group take 1gm of magnesium then second group take 2gm of magnesium and finally third group take 3gm of magnesium Researchers will compare \[ 3 groups \] to see if \[ magnesium has effects in prevention cisplatin nephrotoxicity\].
Timeline
- Start
- 2022-10-01
- Primary completion
- 2025-02-27
- Completion
- 2025-03-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Magnesium Sulfate | Other / unclassified | 1000 mg | Intravenous |
| Comparator | Magnesium Sulfate | Other / unclassified | 2000 mg | Intravenous |
| Comparator | Magnesium Sulfate | Other / unclassified | 3000 mg | Intravenous |
| Comparator | Cisplatin | Other / unclassified | 40 mg/m2 | Intravenous |