drugset / Trial / NCT05586763
Comparison of Efficacy of Metoclopramide , Promethazine and Prochloroperazine in the Treatment of Vertigo.
RandomizedParallel-groupTriple-blindTreatment
Summary
Background: Vertigo as acute symptom seem to be one of most common presentation in ED, can be treated in ED with multiple medication . Objective: This study aimed to compare the therapeutic efficacy of metoclopramide, promethazine and prochloroperazine in patients presenting with signs and symptoms suggestive of acute peripheral vertigo to the ED . Methods: A 3-arm multi-center, randomized, triple-blind, controlled study comparing three treatments for acute vertigo in three medical centers : AlNahdha hospital Oman , Sohar Hospital Oman and AFH hospital Oman. Oman From February 2022 to August 2024.
Timeline
- Start
- 2022-02-01
- Primary completion
- 2024-12-28
- Completion
- 2024-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Metoclopramide | Small molecule | 10 mg | Intramuscular |
| Comparator | Prochloroperazine | Unknown | 12.5 mg | Intramuscular |
| Comparator | Promethazine | Small molecule | 25 mg | Intramuscular |