Hyaluronic Acid for the Treatment of Damaged Nipples in Breastfeeding Women

Phase 4 Recruiting 160 enrolled Specijalisticka Pedijatrijska Ordinacija prim.mr.sc. Maja Stimac, Specijalist Pedijatrije Sspecijalnosti Neonatologije

RandomizedParallel-groupDouble-blindTreatment

Summary

Previous studies have shown that application of hyaluronic acid preparations to wounds of the skin and mucosa have a beneficial effect. There is a lack of studies showing the effect of applying hyaluronic acid preparations to treat damaged nipple skin in breastfeeding mothers. This study aims to determine the effect of applying a hyaluronic acid preparation to damaged nipple skin in breastfeeding women.

Timeline

Start: 2023-01-09
Primary completion: 2025-12
Completion: 2026-02

Publications

Background Tait P. Nipple pain in breastfeeding women: causes, treatment, and prevention strategies. J Midwifery Womens Health. 2000 May-Jun;45(3):212-5. doi: 10.1016/s1526-9523(00)00011-8.
Background Abou-Dakn M, Fluhr JW, Gensch M, Wockel A. Positive effect of HPA lanolin versus expressed breastmilk on painful and damaged nipples during lactation. Skin Pharmacol Physiol. 2011;24(1):27-35. doi: 10.1159/000318228. Epub 2010 Aug 18.
Background Shaharudin A, Aziz Z. Effectiveness of hyaluronic acid and its derivatives on chronic wounds: a systematic review. J Wound Care. 2016 Oct 2;25(10):585-592. doi: 10.12968/jowc.2016.25.10.585.
Background Torretta S, Marchisio P, Rinaldi V, Carioli D, Nazzari E, Pignataro L. Endoscopic and clinical benefits of hyaluronic acid in children with chronic adenoiditis and middle ear disease. Eur Arch Otorhinolaryngol. 2017 Mar;274(3):1423-1429. doi: 10.1007/s00405-016-4327-4. Epub 2016 Oct 1.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sodium Hyaluronate	Other / unclassified	0.2 %	Topical

Indications

No indication recorded.