drugset / Trial / NCT05596617
Safety and Efficacy of Medications COVID-19
Non-randomizedSequentialOpen-labelTreatment
Summary
We performed a quasi-experimental open-label pragmatic study alternating standard of care (SOC) and oral bedtime melatonin (OBM) at different high doses over 4 consecutive time periods enrolling all consecutive RT-PCR SARS-CoV-2 severe Covid-19 admissions.
Timeline
- Start
- 2020-04-22
- Primary completion
- 2021-05-31
- Completion
- 2022-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Melatonin | Small molecule | 50 mg | Oral |
| Subject | Melatonin | Small molecule | 100 mg | Oral |
| Subject | Melatonin | Small molecule | 200 mg | Oral |