drugset / Trial / NCT05596617

Safety and Efficacy of Medications COVID-19

NCT05596617

Completed 335 enrolled Hospital San Carlos, Madrid
Non-randomizedSequentialOpen-labelTreatment

Summary

We performed a quasi-experimental open-label pragmatic study alternating standard of care (SOC) and oral bedtime melatonin (OBM) at different high doses over 4 consecutive time periods enrolling all consecutive RT-PCR SARS-CoV-2 severe Covid-19 admissions.

Timeline

Start
2020-04-22
Primary completion
2021-05-31
Completion
2022-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Melatonin Small molecule 50 mg Oral
Subject Melatonin Small molecule 100 mg Oral
Subject Melatonin Small molecule 200 mg Oral

Indications