drugset / Trial / NCT05605002
Efficacy and Safety of Intradermal Acupuncture for Major Depressive Disorder
Unknown
90 enrolled
Xiaomei Shao
First People's Hospital of Hangzhou · collabThe First Affiliated Hospital of Zhejiang Chinese Medical University · collabZhejiang Provincial Tongde Hospital · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
Major depressive disorder (MDD) is a common mental illness that severely affects the health and quality of life of patients. Treatment with acupuncture alone or a combination of appropriate adjuncts has been reported to be significantly effective in reducing the severity of MDD, relieving patients' somatic symptoms and improving sleep. This study will focus on the intradermal acupuncture, which is more convenient, gentler and has longer lasting effects. The aim is to study the efficacy and safety of intradermal acupuncture for MDD, and to preliminarily explore the central nervous mechanisms by which it exerts its therapeutic effects.
Timeline
- Start
- 2022-01-01
- Primary completion
- 2025-12-30
- Completion
- 2025-12-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Citalopram | Small molecule | — | Oral |
| Background | Fluoxetine | Small molecule | — | Oral |
| Background | Paroxetine | Small molecule | — | Oral |
| Background | Sertraline | Small molecule | — | Oral |