Citalopram

also known as Celexa · Citalopram hydrobromide · Citalopram HBr · CIT · Citalopram, Celexa · CelexaTM · cipralex · Cipramil · +4 more

Small molecule

Developed for: depressive disorder · major depressive disorder · acute coronary syndrome · Alzheimer disease · anxiety · dementia · schizophrenia · stroke disorder
+35 more
· autism spectrum disorder · cocaine dependence · gastroesophageal reflux disease · obsessive-compulsive disorder · Parkinson disease · traumatic brain injury · alcohol abuse · alcohol dependence · asthma · autism · bipolar disorder · circadian rhythm sleep disorder, delayed sleep phase type · cocaine abuse · dysthymic disorder · fibromyalgia · Friedreich ataxia · frontotemporal dementia · Huntington disease · irritable bowel syndrome · myalgic encephalomeyelitis/chronic fatigue syndrome · panic disorder · prurigo nodularis · rheumatoid arthritis · schizophreniform disorder · vascular dementia · bipolar depression · borderline personality disorder · burning mouth syndrome · ischemic stroke · mood disorder · myocardial infarction · myofascial pain syndrome · neurotic depression · premature ejaculation · temporomandibular joint disorder
Investigated by: National Institute of Mental Health (NIMH) · University of Oxford · National Heart, Lung, and Blood Institute (NHLBI) · New York State Psychiatric Institute · University of Pittsburgh · Actavis Inc.
+138 more
· National Institute on Drug Abuse (NIDA) · Sunnybrook Health Sciences Centre · University of Michigan · Centre for Addiction and Mental Health · Columbia University · Emory University · Indiana University · Massachusetts General Hospital · Mayo Clinic · National Institute of Mental Health and Neuro Sciences, India · National Institute on Aging (NIA) · Ontario Mental Health Foundation · Stanford University · The University of Texas Health Science Center, Houston · Torrent Pharmaceuticals Limited · Universitaire Ziekenhuizen KU Leuven · University of Bath · University of North Carolina, Chapel Hill · 59th Medical Wing · Alliance for Clinical Trials in Oncology · Alzheimer Society of Canada · Amsterdam UMC, location VUmc · Artesis University College, Antwerp · Asthma UK · Big Health Inc. · Boehringer Ingelheim · Boston University · Bruce Pollock · CIHR Canadian HIV Trials Network · California Pacific Medical Center Research Institute · Canadian Institutes of Health Research (CIHR) · Capital Medical University · Catalan Institute of Oncology · Central Hospital, Nancy, France · Centre Hospitalier Universitaire Vaudois · Centre de Recherche du Centre Hospitalier de l'Université de Montréal · Chang Gung Memorial Hospital · Charite University, Berlin, Germany · Chih-Wei Tang · Ciusss de L'Est de l'Île de Montréal · Cure Huntington's Disease Initiative (CHDI) · Dalian Seventh People's Hospital · Danish University Antidepressant Group · Demensforbundet, Norway · Ege University · First Hospital of China Medical University · French National Institute of Health and Medical Research · German Research Foundation · Gitte Moos Knudsen · Hadassah Medical Organization · Hamilton Health Sciences Corporation · Hannover Medical School · Henry Ford Health System · HolsboerMaschmeyer NeuroChemie GmbH · Hospices Civils de Lyon · Hospital Regional 1o de Octubre · Hospital Universitari de Bellvitge · Hunter Holmes McGuire VA Medical Center · Idorsia Pharmaceuticals Ltd. · Innlandet Hospital Trust · Irish Cancer Society · JHSPH Center for Clinical Trials · James A. Haley Veterans Administration Hospital · Jing-Ho Mental Hospital, Taiwan · John V. Campo, M.D. · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · King's College London · Liam Heaney · Marina Klein · Max-Planck-Institute of Psychiatry · McMaster University · Mclean Hospital · Medical University of Vienna · Medtronic - MITG · all 144 on the full record

Regulatory milestones approvals, filings & regulatory actions · 1 recorded

Milestone	Jurisdiction	Brand	Indication	Date	Sentence it was read from
Approved	US (FDA)	CELEXA	—	1998-07-17	fda.gov ↗

Trials 100 · started per year

today

US approved 1998

1995199619971998199920002001200220032004200520062007200820092010201120122013201420152016201720182019202020212022202320242025202620272028

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 02 trials
Phase 0	NCT06796946	Jun → Dec 2026 expected	—	University of Huelva	Not yet recruiting	No outcome recorded
Phase 0	NCT02269540	Oct 2014 → Jun 2018	major depressive disorder	Centre for Addiction and Mental Health	Completed	No outcome recorded
Phase 114 trials
Phase 1	NCT04097288	Sep 2019 → Feb 2020	female stress incontinence	University Hospital Bispebjerg and Frederiksberg	Completed	No outcome recorded
Phase 1	NCT03907215	Apr → Jun 2019	—	Idorsia Pharmaceuticals Ltd.	Completed	No outcome recorded
Phase 1	NCT03854578	Mar → Aug 2019	major depressive disorder	Boehringer Ingelheim	Completed	No outcome recorded
Phase 1	NCT02092974	Apr → Dec 2014	—	Charite University, Berlin, Germany	Completed	No outcome recorded
Phase 1	NCT01978782	Jan → Apr 2014	HIV infectious disease, depressive disorder	Radboud University Medical Center	Completed	No outcome recorded
Phase 1	NCT01951053	Jan → May 2010	—	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.	Completed	No outcome recorded
Phase 1	NCT00538889	Aug → Nov 2007	—	Wyeth is now a wholly owned subsidiary of Pfizer	Completed	No outcome recorded
Phase 1	NCT00609531	Jan 2007 → Aug 2009	autism spectrum disorder	University of North Carolina, Chapel Hill	Completed	No outcome recorded
Phase 1	NCT00613470	Mar 2005 → May 2013	depressive disorder	Mayo Clinic	Completed	No outcome recorded
Phase 1	NCT00865943	Jul → Aug 2003	—	Actavis Inc.	Completed	No outcome recorded
Phase 1	NCT00864890	Jun → Jul 2003	—	Actavis Inc.	Completed	No outcome recorded
Phase 1	NCT00865085	Jun → Jul 2003	—	Actavis Inc.	Completed	No outcome recorded
Phase 1	NCT00939835	—	—	Torrent Pharmaceuticals Limited	Completed	No outcome recorded
Phase 1	NCT00940238	—	—	Torrent Pharmaceuticals Limited	Completed	No outcome recorded

Phase 1/23 trials
Phase 1/2	NCT06017037	May 2023 → May 2024	atypical depressive disorder	University of Oxford	Unknown	No outcome recorded
Phase 1/2	NCT01667744	Jan → Feb 2016	acute coronary syndrome	Henry Ford Health System	Withdrawn	No outcome recorded
Phase 1/2	NCT01032018	Jan 2010 → Jan 2012	acute coronary syndrome, depressive disorder	Columbia University	Completed	No outcome recorded
Phase 217 trials
Phase 2	NCT05063604	May 2022	breast cancer, major depressive disorder	Hospital Universitari de Bellvitge	Terminated	No outcome recorded
Phase 2	NCT04766229	Jun 2021 → Nov 2022	cancer, insomnia	University College Dublin	Completed	No outcome recorded
Phase 2	NCT04497168	Apr 2021 → Mar 2026	Parkinson disease	University of Michigan	Completed	No outcome recorded
Phase 2	NCT03222570	Feb 2018 → Apr 2024	depressive disorder	University of Minnesota	Completed	No outcome recorded
Phase 2	NCT03899285	Jan → Dec 2018	major depressive disorder	Ciusss de L'Est de l'Île de Montréal	Completed	No outcome recorded
Phase 2	NCT02458690	Jul 2015 → Aug 2019	coronary artery disorder, dysthymic disorder, major depressive disorder, stroke disorder	Indiana University	Completed	No outcome recorded
Phase 2	NCT02113943	Apr → Jun 2014	—	French National Institute of Health and Medical Research	Completed	No outcome recorded
Phase 2	NCT02000726	Jul 2013 → Jun 2014	depressive disorder	University of Michigan	Withdrawn	No outcome recorded
Phase 2	NCT02080832	Feb 2010 → Feb 2016	cocaine dependence	Virginia Commonwealth University	Completed	No outcome recorded
Phase 2	NCT00742573	Aug 2008 → Jan 2014	major depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 2	NCT00218036	Jul 2006 → Feb 2010	cocaine abuse, opiate dependence	The University of Texas Health Science Center, Houston	Terminated	No outcome recorded
Phase 2	NCT00271596	Nov 2005 → Apr 2011	Huntington disease, choreatic disease	University of Iowa	Completed	No outcome recorded
Phase 2	NCT00249405	Feb 2005 → Oct 2010	alcohol abuse, alcohol dependence	University of Cincinnati	Completed	No outcome recorded
Phase 2	NCT00086645	Apr 2004 → Oct 2006	autism	Boston University	Completed	No outcome recorded
Phase 2	NCT00297505	Apr 2001 → Nov 2004	cocaine dependence	National Institute on Drug Abuse (NIDA)	Completed	No outcome recorded
Phase 2	NCT00477165	Apr 2001 → Jun 2009	irritable bowel syndrome	Stanford University	Completed	No outcome recorded
Phase 2	NCT00073658	Jan 2000 → Jun 2005	dementia	University of Pittsburgh	Completed	No outcome recorded

Phase 2/33 trials
Phase 2/3	NCT00962039	Jul 2004 → Apr 2010	anxiety	John V. Campo, M.D.	Completed	No outcome recorded
Phase 2/3	NCT00080158	Mar 2004 → Jun 2007	depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 2/3	NCT00018902	Jan 2001 → Mar 2007	depressive disorder	University of Pittsburgh	Completed	No outcome recorded
Phase 39 trials
Phase 3	NCT05041582	Sep 2021 → Aug 2024	stroke disorder	Chih-Wei Tang	Unknown	No outcome recorded
Phase 3	NCT02374567	Jan 2015 → Jun 2017	anxiety disorder, dementia, depressive disorder, schizophrenia +1	Hannover Medical School	Terminated	No outcome recorded
Phase 3	NCT00898807	Jul 2009 → Sep 2013	Alzheimer disease	JHSPH Center for Clinical Trials	Completed	No outcome recorded
Phase 3	NCT00317746	Nov 2006 → Mar 2012	HIV infectious disease, depressive disorder, hepatitis C virus infection	Marina Klein	Completed	No outcome recorded
Phase 3	NCT00363909	Nov 2006 → Jun 2007	breast cancer	Alliance for Clinical Trials in Oncology	Completed	No outcome recorded
Phase 3	NCT00361218	Oct 2005 → Dec 2008	major depressive disorder	Massachusetts General Hospital	Completed	No outcome recorded
Phase 3	NCT00249886	Sep 2002 → Nov 2006	major depressive disorder	Sunnybrook Health Sciences Centre	Withdrawn	No outcome recorded
Phase 3	NCT00000368	Feb 1999 → Jul 2004	agoraphobia, panic disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 3	NCT00009204	Sep 1995 → Apr 2000	Alzheimer disease, vascular dementia	Bruce Pollock	Completed	No outcome recorded
Phase 424 trials
Phase 4	NCT03499171	May 2019 → Apr 2021	gastroesophageal reflux disease	Universitaire Ziekenhuizen KU Leuven	Unknown	No outcome recorded
Phase 4	NCT03993535	Oct 2018 → Apr 2023	obsessive-compulsive disorder	University of Sao Paulo	Completed	No outcome recorded
Phase 4	NCT03746691	Feb → Jul 2017	gastroesophageal reflux disease	Universitaire Ziekenhuizen KU Leuven	Completed	No outcome recorded
Phase 4	NCT02711215	May 2015 → Jan 2020	major depressive disorder	Medical University of Vienna	Unknown	No outcome recorded
Phase 4	NCT02473250	Jan 2015 → Dec 2019	bipolar disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 4	NCT01916824	Aug 2013 → Dec 2015	major depressive disorder	Emory University	Completed	No outcome recorded
Phase 4	NCT01716221	Oct 2012 → Mar 2013	Friedreich ataxia	University of Colorado, Denver	Completed	No outcome recorded
Phase 4	NCT01796132	Aug 2012 → Dec 2016	depressive disorder, lactation disease	Centre Hospitalier Universitaire Vaudois	Unknown	No outcome recorded
Phase 4	NCT01557946	Mar 2012 → Sep 2015	major depressive disorder	Mclean Hospital	Completed	No outcome recorded
Phase 4	NCT01436643	Nov 2011 → Sep 2013	depressive disorder, relapsing-remitting multiple sclerosis	Novartis Pharmaceuticals	Terminated	No outcome recorded
Phase 4	NCT02237937	Sep 2011 → Dec 2014	major depressive disorder	HolsboerMaschmeyer NeuroChemie GmbH	Unknown	No outcome recorded
Phase 4	NCT02178696	Jan 2011 → Oct 2015	depressive disorder	University of Michigan	Completed	No outcome recorded
Phase 4	NCT01099592	Nov 2010 → Apr 2011	acute coronary syndrome, major depressive disorder	University of Montreal Hospital Centre (CHUM)	Terminated	No outcome recorded
Phase 4	NCT01041274	Jan 2010 → Dec 2014	schizophrenia, schizophreniform disorder	NYU Langone Health	Completed	No outcome recorded
Phase 4	NCT00433121	Sep 2006 → Aug 2007	dementia	Innlandet Hospital Trust	Completed	No outcome recorded
Phase 4	NCT00376051	Sep 2006 → Jul 2009	frontotemporal dementia	Sunnybrook Health Sciences Centre	Completed	No outcome recorded
Phase 4	NCT00269334	Dec 2005 → Nov 2007	major depressive disorder	National Health Research Institutes, Taiwan	Unknown	No outcome recorded
Phase 4	NCT00162916	May 2005 → May 2008	depressive disorder	Ontario Neurotrauma Foundation	Unknown	No outcome recorded
Phase 4	NCT00893256	Dec 2004 → Sep 2007	schizophrenia	National Institute of Mental Health and Neuro Sciences, India	Completed	No outcome recorded
Phase 4	NCT00118430	Sep 2004 → Jul 2008	depressive disorder	Indiana University	Completed	No outcome recorded
Phase 4	NCT00108563	Oct 2003 → Sep 2006	depressive disorder, hepatitis C virus infection	US Department of Veterans Affairs	Completed	No outcome recorded
Phase 4	NCT00254007	Jul 2003 → Dec 2005	major depressive disorder, traumatic brain injury	Sunnybrook Health Sciences Centre	Completed	No outcome recorded
Phase 4	NCT00157547	Apr 2003 → Aug 2006	major depressive disorder	Massachusetts General Hospital	Completed	No outcome recorded
Phase 4	NCT00021528	Jul 2001 → Sep 2006	major depressive disorder	National Institute of Mental Health (NIMH)	Completed	No outcome recorded

Phase not applicable28 trials
—	NCT06949644	Sep 2025 → Jul 2029 expected	circadian rhythm sleep disorder, delayed sleep phase type	Northwestern University	Recruiting	No outcome recorded
—	NCT06412315	Feb 2025 → Oct 2026 expected	depressive disorder	University of Oxford	Recruiting	No outcome recorded
—	NCT05627154	May 2021 → Nov 2023	anxiety, depressive disorder	University of Oxford	Completed	No outcome recorded
—	NCT05346445	Jan → Nov 2021	—	Hospital Regional 1o de Octubre	Completed	No outcome recorded
—	NCT04590612	Jan 2021 → Jan 2022	Parkinson disease, depressive disorder	Western University, Canada	Unknown	No outcome recorded
—	NCT04169230	Oct 2019 → Sep 2020	depressive disorder	University of Oxford	Unknown	No outcome recorded
—	NCT04161209	Oct 2019 → Sep 2020	depressive disorder	University of Oxford	Unknown	No outcome recorded
—	NCT06212284	Feb → Nov 2018	—	University of Sussex	Completed	No outcome recorded
—	NCT04776226	Feb 2017 → Mar 2018	depressive disorder, stroke disorder	Ege University	Completed	No outcome recorded
—	NCT04145076	Dec 2014 → Feb 2023	autism spectrum disorder	King's College London	Unknown	No outcome recorded
—	NCT02285699	Nov 2014 → Mar 2016	obsessive-compulsive disorder	McMaster University	Completed	No outcome recorded
—	NCT02023567	Nov 2013 → Dec 2016	major depressive disorder	Peking University	Unknown	No outcome recorded
—	NCT01778686	Jan → Nov 2013	—	Gitte Moos Knudsen	Completed	No outcome recorded
—	NCT01153165	Nov 2010 → Jun 2012	asthma	Liam Heaney	Unknown	No outcome recorded
—	NCT01154647	Sep 2010 → Sep 2012	fibromyalgia, myalgic encephalomeyelitis/chronic fatigue syndrome, rheumatoid arthritis	Vrije Universiteit Brussel	Unknown	No outcome recorded
—	NCT00876226	May 2010 → Sep 2012	short bowel syndrome	University of Nebraska	Withdrawn	No outcome recorded
—	NCT00930293	Jul 2009 → Jun 2012	anxiety, depressive disorder	University of Pittsburgh	Completed	No outcome recorded
—	NCT01216449	Apr 2009 → Oct 2011	—	Rotman Research Institute at Baycrest	Terminated	No outcome recorded
—	NCT00838305	Feb → Dec 2009	—	California Pacific Medical Center Research Institute	Completed	No outcome recorded
—	NCT00896441	Feb 2009 → Oct 2013	depressive disorder	Stanford University	Terminated	No outcome recorded
—	NCT00817011	Apr 2006 → Dec 2016	depressive disorder	Samsung Medical Center	Unknown	No outcome recorded
—	NCT00993876	Aug 2005 → Aug 2008	—	Zentrum für Integrative Psychiatrie	Completed	No outcome recorded
—	NCT00188396	Apr 2004 → Oct 2008	major depressive disorder	University Health Network, Toronto	Completed	No outcome recorded
—	NCT00208572	Nov 2003 → Feb 2008	traumatic brain injury	Walter Reed Army Medical Center	Unknown	No outcome recorded
—	NCT00217828	Mar 2002 → Feb 2003	heart disorder	University of Pittsburgh	Completed	No outcome recorded
—	NCT00015548	Mar 2001 → Oct 2004	Alzheimer disease	National Institute of Mental Health (NIMH)	Completed	No outcome recorded
—	NCT01575158	Oct 1997 → Sep 2007	depressive disorder	University of Aarhus	Completed	No outcome recorded
—	NCT00532519	—	prurigo nodularis	Hadassah Medical Organization	Unknown	No outcome recorded

Also used as a comparator or background therapy in 95 trials

Phase	Registry id	Dates	Indication	Sponsor	Status	Outcome
Phase 04 trials
Phase 0	NCT03607331 Comparator	Sep 2018 → Jul 2019	depressive disorder	China Academy of Chinese Medical Sciences	Unknown	No outcome recorded
Phase 0	NCT03282110 Comparator	Nov 2017 → Jun 2018	neurotic depression	China Academy of Chinese Medical Sciences	Unknown	No outcome recorded
Phase 0	NCT04846829 Comparator	Apr 2017 → Apr 2028 expected	major depressive disorder	University of California, Los Angeles	Active not recruiting	No outcome recorded
Phase 0	NCT01725048 Comparator	Jan 2011 → May 2012	major depressive disorder, neoplasm	UNC Lineberger Comprehensive Cancer Center	Completed	No outcome recorded
Phase 17 trials
Phase 1	NCT06192589 Comparator	Feb → Sep 2024	drug-induced liver injury	Food and Drug Administration (FDA)	Completed	No outcome recorded
Phase 1	NCT03516604 Comparator	May 2018 → Jul 2022	depressive disorder	University of Oxford	Completed	No outcome recorded
Phase 1	NCT01657760 Comparator	May 2014 → Aug 2017	alcohol dependence	VA Office of Research and Development	Completed	No outcome recorded
Phase 1	NCT01396720 Comparator	Sep 2011 → Dec 2012	—	Hadassah Medical Organization	Completed	No outcome recorded
Phase 1	NCT01367756 Background	May → Sep 2011	—	Hoffmann-La Roche	Completed	No outcome recorded
Phase 1	NCT01424384 Comparator	Sep 2008 → Apr 2009	mixed anxiety and depressive disorder	GlaxoSmithKline	Completed	No outcome recorded
Phase 1	NCT00676039 Comparator	Nov 2007 → Jul 2008	—	University of Ottawa	Completed	No outcome recorded

Phase 1/22 trials
Phase 1/2	NCT05271084 Background	Nov 2021 → Feb 2022	major depressive disorder	Hawler Medical University	Completed	No outcome recorded
Phase 1/2	NCT00612807 Background	Jul 2006 → Jun 2010	major depressive disorder	Duke University	Completed	No outcome recorded
Phase 213 trials
Phase 2	NCT03321526 Background	Dec 2017 → Jun 2019	major depressive disorder	Janssen Research & Development, LLC	Completed	No outcome recorded
Phase 2	NCT01937182 Comparator	Sep 2013 → Dec 2016	ischemic stroke	University of Aarhus	Completed	No outcome recorded
Phase 2	NCT01742832 Comparator	May 2013 → Mar 2016	major depressive disorder	University of Chicago	Completed	No outcome recorded
Phase 2	NCT01254305 Comparator	Apr 2011 → Jul 2012	major depressive disorder	Forest Laboratories	Completed	No outcome recorded
Phase 2	NCT01535573 Comparator	Dec 2010 → Jul 2016	cocaine dependence	Joy Schmitz	Completed	No outcome recorded
Phase 2	NCT01189812 Comparator	Mar 2010 → Jan 2011	borderline personality disorder, dysthymic disorder, major depressive disorder	Columbia Northwest Pharmaceuticals	Completed	No outcome recorded
Phase 2	NCT01179568 Comparator	Mar 2010 → Feb 2015	—	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 2	NCT00854100 Background	Jun 2009 → Dec 2010	major depressive disorder	Forest Laboratories	Completed	No outcome recorded
Phase 2	NCT00977353 Comparator	Apr 2009 → Jul 2011	major depressive disorder	China Medical University Hospital	Completed	No outcome recorded
Phase 2	NCT00794040 Comparator	Nov 2008 → Feb 2018	attention deficit-hyperactivity disorder, disruptive behavior disorder, mood disorder	National Institute of Mental Health (NIMH)	Completed	No outcome recorded
Phase 2	NCT00692445 Comparator	Jun 2008 → May 2009	major depressive disorder	Targacept Inc.	Completed	No outcome recorded
Phase 2	NCT00672659 Comparator	Feb 2008 → Jan 2009	major depressive disorder	PharmaNeuroBoost N.V.	Completed	No outcome recorded
Phase 2	NCT00774813 Comparator	Oct 2007 → May 2008	depressive disorder	Kalaco Scientific, Inc.	Completed	No outcome recorded

Phase 2/33 trials
Phase 2/3	NCT04777838 Comparator	Mar → May 2021	myofascial pain syndrome, temporomandibular joint disorder	University of Coimbra	Unknown	No outcome recorded
Phase 2/3	NCT01109030 Comparator	Apr 2010 → Oct 2011	major depressive disorder	Tehran University of Medical Sciences	Completed	No outcome recorded
Phase 2/3	NCT00562861 Comparator	Nov 2007 → Jul 2014	bipolar depression	Tufts Medical Center	Completed	No outcome recorded
Phase 314 trials
Phase 3	NCT06025474 Comparator	Jan → Oct 2023	burning mouth syndrome	Federico II University	Unknown	No outcome recorded
Phase 3	NCT04476030 Background	Nov 2020 → Oct 2021	major depressive disorder	Biogen	Completed	No outcome recorded
Phase 3	NCT03538691 Background	Jul 2018 → Jul 2022	major depressive disorder	Otsuka Pharmaceutical Development & Commercialization, Inc.	Completed	No outcome recorded
Phase 3	NCT02624102 Background	Sep 2015 → Dec 2017	major depressive disorder	Hemanny, Curt, M.D.	Completed	No outcome recorded
Phase 3	NCT02400346 Background	Mar 2015 → Jun 2016	major depressive disorder	H. Lundbeck A/S	Completed	No outcome recorded
Phase 3	NCT02279953 Background	Oct 2014 → Apr 2016	major depressive disorder	H. Lundbeck A/S	Completed	No outcome recorded
Phase 3	NCT01838876 Background	Apr 2013 → Jul 2015	major depressive disorder	Forest Laboratories	Completed	No outcome recorded
Phase 3	NCT01715805 Background	Nov 2012 → Jun 2016	major depressive disorder	Forest Laboratories	Completed	No outcome recorded
Phase 3	NCT02179268 Comparator	Mar 2012 → Apr 2014	osteoporosis	Guiyang Medical University	Completed	No outcome recorded
Phase 3	NCT01312922 Comparator	Sep 2011 → Nov 2012	major depressive disorder	PharmaNeuroBoost N.V.	Completed	No outcome recorded
Phase 3	NCT00351910 Background	May 2006 → Apr 2007	major depressive disorder	AstraZeneca	Completed	No outcome recorded
Phase 3	NCT00074815 Background	Sep 2003 → Nov 2009	obsessive-compulsive disorder	Duke University	Completed	No outcome recorded
Phase 3	NCT00067301 Background	Sep 2003 → Apr 2007	major depressive disorder	National Center for Complementary and Integrative Health (NCCIH)	Completed	No outcome recorded
Phase 3	NCT00044798 Background	Sep 2001 → Mar 2007	depressive disorder	University of Iowa	Completed	No outcome recorded

Phase 431 trials
Phase 4	NCT07047651 Background	Jun 2025 → Dec 2027 expected	treatment-refractory schizophrenia	Dr. Stavroula Rakitzi	Active not recruiting	No outcome recorded
Phase 4	NCT06740188 Comparator	Jan 2025 → Dec 2026 expected	—	Tongji University	Recruiting	No outcome recorded
Phase 4	NCT07113145 Comparator	Jun 2024 → Jan 2025	premature ejaculation	Beni-Suef University	Completed	No outcome recorded
Phase 4	NCT05735756 Comparator	Jan → Apr 2022	—	Academic Medical Center - University of Amsterdam	Terminated	No outcome recorded
Phase 4	NCT05148169 Background	Jan 2020 → Dec 2022	major depressive disorder	Shanghai Mental Health Center	Unknown	No outcome recorded
Phase 4	NCT04975724 Background	Apr 2019 → Oct 2025	major depressive disorder	Fidia Farmaceutici s.p.a.	Unknown	No outcome recorded
Phase 4	NCT03779789 Comparator	Feb 2019 → Feb 2023	major depressive disorder	Azienda Ospedaliera Universitaria Integrata Verona	Completed	No outcome recorded
Phase 4	NCT02386475 Comparator	Jan 2015 → Mar 2017	stroke disorder	Hospital de Granollers	Completed	No outcome recorded
Phase 4	NCT02825342 Comparator	Mar 2014 → Aug 2017	myocardial infarction	Evangelismos Hospital	Terminated	No outcome recorded
Phase 4	NCT02022709 Comparator	Jan 2014 → Nov 2017	obsessive-compulsive disorder	Shanghai Mental Health Center	Completed	No outcome recorded
Phase 4	NCT01903447 Comparator	Dec 2013 → Feb 2018	anxiety	University of Illinois at Chicago	Completed	No outcome recorded
Phase 4	NCT02028026 Comparator	Apr 2013 → Feb 2015	anxiety, major depressive disorder	Massachusetts General Hospital	Withdrawn	No outcome recorded
Phase 4	NCT03278938 Comparator	Jun 2012 → Jan 2016	depressive disorder	New York State Psychiatric Institute	Withdrawn	No outcome recorded
Phase 4	NCT01764867 Comparator	Jun 2012 → Oct 2014	major depressive disorder	Shanghai Mental Health Center	Unknown	No outcome recorded
Phase 4	NCT01460212 Comparator	Dec 2011 → Dec 2014	major depressive disorder	Nanjing Medical University	Unknown	No outcome recorded
Phase 4	NCT01473381 Comparator	Dec 2011 → Jun 2013	major depressive disorder	Forest Laboratories	Completed	No outcome recorded
Phase 4	NCT01658228 Background	Sep 2011 → Jan 2016	cognitive impairment with or without cerebellar ataxia, depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 4	NCT01032083 Comparator	Jul 2011 → Dec 2014	schizophrenia	Imperial College London	Completed	No outcome recorded
Phase 4	NCT01919216 Comparator	Jan 2010 → Jun 2016	major depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 4	NCT01305707 Comparator	Jul 2009 → Jul 2014	major depressive disorder	Hospital Universitari de Bellvitge	Terminated	No outcome recorded
Phase 4	NCT00834834 Comparator	Mar 2009 → Aug 2015	borderline personality disorder	New York State Psychiatric Institute	Completed	No outcome recorded
Phase 4	NCT01300364 Comparator	Nov 2008 → Dec 2011	schizophrenia	Fundació Sant Joan de Déu	Unknown	No outcome recorded
Phase 4	NCT00955474 Comparator	Sep 2008 → Jan 2013	major depressive disorder	Massachusetts General Hospital	Terminated	No outcome recorded
Phase 4	NCT00594269 Comparator	Aug 2008 → Dec 2010	dementia	Innlandet Hospital Trust	Completed	No outcome recorded
Phase 4	NCT00666757 Comparator	May 2008 → Feb 2009	depressive disorder	Eli Lilly and Company	Completed	No outcome recorded
Phase 4	NCT00602290 Comparator	Feb 2008 → Jan 2013	depressive disorder	University of California, Los Angeles	Completed	No outcome recorded
Phase 4	NCT00825825 Comparator	May 2007 → Apr 2011	—	Michael Henry, MD	Completed	No outcome recorded
Phase 4	NCT00680602 Comparator	Jan 2006 → Sep 2008	obsessive-compulsive disorder	University of Sao Paulo	Completed	No outcome recorded
Phase 4	NCT00254020 Background	Jun 2005 → Jan 2011	depressive disorder	Sunnybrook Health Sciences Centre	Completed	No outcome recorded
Phase 4	NCT00221494 Background	Jan 2004 → Jun 2006	depressive disorder	Mark Frye	Withdrawn	No outcome recorded
Phase 4	NCT00047671 Comparator	Jun 2002 → Nov 2006	depressive disorder	National Institute of Mental Health (NIMH)	Completed	No outcome recorded

Phase not applicable21 trials
—	NCT05957094 Comparator	Aug 2023 → Aug 2024	depressive disorder, metabolic disease involving other neurotransmitter deficiency	University of British Columbia	Unknown	No outcome recorded
—	NCT06358014 Background	May 2023 → Dec 2024	depressive disorder	Xiao Wang	Unknown	No outcome recorded
—	NCT05832619 Background	Nov 2022 → Dec 2025	major depressive disorder	Xiaomei Shao	Unknown	No outcome recorded
—	NCT05720637 Background	Nov 2022 → Jan 2024	major depressive disorder	Xiaomei Shao	Completed	No outcome recorded
—	NCT05528224 Background	Sep 2022 → Aug 2023	obsessive-compulsive disorder	Shanghai Mental Health Center	Terminated	No outcome recorded
—	NCT05605002 Background	Jan 2022 → Dec 2025	major depressive disorder	Xiaomei Shao	Unknown	No outcome recorded
—	NCT05588102 Background	May 2021 → May 2023	cognitive disorder	Capital Medical University	Completed	No outcome recorded
—	NCT03558256 Background	May 2016 → Dec 2018	major depressive disorder	Shanghai Mental Health Center	Unknown	No outcome recorded
—	NCT02655354 Background	Oct 2015 → Nov 2019	alcohol-related disorders, brain injury, cognitive impairment with or without cerebellar ataxia, depressive disorder +1	University of Washington	Completed	No outcome recorded
—	NCT02262156 Comparator	Aug → Oct 2014	depressive disorder, temporal lobe epilepsy	El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez	Completed	No outcome recorded
—	NCT01944657 Comparator	Sep 2013 → Dec 2015	major depressive disorder	Sheppard Pratt Health System	Withdrawn	No outcome recorded
—	NCT01896349 Background	Apr 2013 → Aug 2014	—	Hospital de Clinicas de Porto Alegre	Unknown	No outcome recorded
—	NCT04355455 Comparator	Jul → Dec 2011	gastroesophageal reflux disease	Universitaire Ziekenhuizen KU Leuven	Completed	No outcome recorded
—	NCT01831440 Background	Jan 2011 → Jan 2014	depressive disorder	Nanjing Medical University	Unknown	No outcome recorded
—	NCT01946607 Comparator	Jul 2009 → Nov 2010	—	University of Oxford	Completed	No outcome recorded
—	NCT00944996 Comparator	Jun 2009 → Jun 2010	major depressive disorder	Tirat Carmel Mental Health Center	Completed	No outcome recorded
—	NCT00564278 Background	Feb 2008 → Aug 2013	depressive disorder	New York State Psychiatric Institute	Completed	No outcome recorded
—	NCT00129467 Background	Feb 2005 → Sep 2009	cancer, depressive disorder	US Department of Veterans Affairs	Completed	No outcome recorded
—	NCT00226694 Comparator	Sep 2003 → Aug 2011	alcohol dependence	University of Cincinnati	Completed	No outcome recorded
—	NCT00048815 Comparator	Feb 2003 → Apr 2007	depressive disorder	Massachusetts General Hospital	Completed	No outcome recorded
—	NCT00047450 Comparator	Sep 2001 → Sep 2006	schizophrenia	Veterans Medical Research Foundation	Completed	No outcome recorded

Evidence & citations 16 cited values

Every value below carries the sentence it was read from. 198 sources stand behind the page.

Field	Value	Cited text
Known as	Citalopram	“we have restricted the IMPACT list of antidepressants to SSRIs (sertraline, escitalopram, paroxetine, fluoxetine, citalopram), duloxetine, bupropion, and mirtazapine. These...” NCT02458690 ↗ 190 “Participants receive only clinical routine antidepressant treatment,Which include fluoxetine (Prozac); sertraline (Zoloft); paroxetine (Paxil); citalopram (Celexa)...” NCT01831440 ↗ “Antidepressant medications may include the following: citalopram (Celexa), escitalopram (Lexapro), paroxetine (Paxil CR), sertraline (Zoloft), venlafaxine XR (Effexor XR),...” NCT00564278 ↗ “Medication group is a control group that can choose to use the serotonin reuptake inhibitors (SSRIs) approved by China food and Drug Administration (SFDA) for the treatment of...” NCT03558256 ↗ “ADT such as citalopram, escitalopram, fluoxetine, sertraline, paroxetine, vilazodone, venlafaxine, desvenlafaxine, duloxetine or bupropion prescribed in accordance with its...” NCT01838876 ↗ “Citalopram, ecitalopram, fluoxetine, sertraline, paroxetine IR, paroxetine CR, venlafaxine IR, venlafaxine XR (extended release), desvenlafaxine, duloxetine, mirtazapine,...” NCT02400346 ↗ “Drug: Antidepressant (citalopram, duloxetine, escitalopram, sertraline, or venlafaxine XR) + cariprazine (0.1-0.3 mg/d) Oral, once daily for 8 weeks following an 8 week...” NCT00854100 ↗ “The dose is 20-60mg/day for fluoxetine, 20-40mg/day for paroxetine, 100-300mg/day for fluvoxamine, 50-200mg/day for sertraline, 20-40mg/day for citalopram, 10-20mg/day for...” NCT05148169 ↗ “Participants will receive SSRI antidepressant (such as, citalopram, escitalopram, fluvoxamine, fluoxetine, paroxetine, sertraline, vilazodone or vortioxetine) as a part of...” NCT03321526 ↗ “Antidepressant medications may include any of the following: citalopram, escitalopram, paroxetine, sertraline, venlafaxine XR, bupropion SR, duloxetine, nortriptyline, and mirtazapine.” NCT00742573 ↗ “approved by the State Food and Drug Administration (CFDA) for the treatment of OCD (i.e., fluoxetine, paroxetine, sertraline and fluvoxamine) as well as citalopram and escitalopram” NCT05528224 ↗ “SSRIs antidepressants, including fluoxetine, paroxetine, sertraline, citalopram, etc., will be administered at oral doses determined by the psychiatrist. Once daily for 6 weeks.” NCT05832619 ↗ “quantifying the range of concentration to citalopram, escitalopram, sertraline, fluoxetine, paroxetine, fluvoxamine, duloxetine and venlafaxine in mother plasma and breast milk” NCT01796132 ↗ “This study uses SSRIs class drugs, including fluoxetine, paroxetine, fluvoxamine, sertraline, citalopram, and escitalopram, with no specific restrictions on the type of drugs.” NCT06358014 ↗ “ADT such as bupropion, citalopram, desvenlafaxine, duloxetine, escitalopram, fluoxetine, sertraline, venlafaxine, paroxetine or vilazodone as prescribed by the physician.” NCT01715805 ↗ “Throughout the study, all subjects will receive either escitalopram (Lexapro) or citalopram (Celexa) on the basis of the study doctor's clinical judgment.” NCT00361218 ↗ “SSRIs antidepressants, including fluoxetine, paroxetine, sertraline, citalopram, etc., will be administered at oral doses determined by the psychiatrist.” NCT05720637 ↗ “SSRIs antidepressants, including fluoxetine, paroxetine, sertraline, citalopram, etc., will be administered at oral doses determined by the psychiatrist.” NCT05605002 ↗ “Patients who are not on a SSRI at the time of enrollment will be prescribed citalopram 10 mg per day for 2 weeks, then 20 mg per day.” NCT00129467 ↗ “Patients with MDD, in use of antidepressants (fluoxetine, citalopram, escitalopram, bupropion, etc.) without psychotherapy.” NCT02624102 ↗ “Received Citalopram hydrobromide, starting with 10 mg once daily for 1 week, followed by 20 mg once daily for 10 weeks” NCT07113145 ↗ “SSRIs (daily dose of at least 20 mg for citalopram, 20 mg for fluoxetine, 100 mg for sertraline, 20 mg for paroxetine)” NCT00612807 ↗ “selective serotonin reuptake inhibitors (fluoxetine, sertraline, citalopram, escitalopram, paroxetine or fluvoxamine)” NCT03993535 ↗ “sertraline: 100-200mg, citalopram 20-40mg, escitalopram 10-20mg, paroxetine 20-60mg; fluoxetine 20-80mg” NCT01903447 ↗ “Patients will receive the "treatment as usual" with a SSRI: sertraline or citalopram.” NCT02262156 ↗ “selective serotonin reuptake inhibitor (SSRI; paroxetine or citalopram; n = 34)” PMID 26663632 ↗ Dec 2015 “Fluoxetine, escitalopram, citalopram, fluvoxamine, or sertraline” NCT03222570 ↗ “paroxetine, fluoxetine, sertraline, escitalopram, citalopram” NCT00944996 ↗ “either citalopram 20 mg/day or fluvoxamine 100 mg/day” PMID 25689244 ↗ Feb 2015 “citalopram (20 mg, increased to 30 to 40 mg)” NCT00118430 ↗ “paroxetine (Paxil); citalopram (Celexa)” NCT01460212 ↗ “escitalopram, citalopram or sertraline” NCT02279953 ↗ “- Citalopram 20-60 mg/d. N06AB04” NCT01305707 ↗ “citalopram (Celexa and others)” NCT01944657 ↗ “Citalopram (Celexa)10-60;” NCT00074815 ↗ “citalopram 20-60mg/day” NCT02023567 ↗ “Citalopram, Celexa” NCT01916824 ↗ “citalopram_Celexa” NCT00817011 ↗ “Citalopram” NCT00864890 ↗ “Citalopram” NCT00865085 ↗ “citalopram” NCT00157547 ↗ NCT02374567 ↗ NCT00562861 ↗ NCT02237937 ↗ NCT00188396 ↗ NCT01473381 ↗ NCT00876226 ↗ NCT00271596 ↗ NCT04161209 ↗ NCT03779789 ↗ NCT06740188 ↗ NCT03278938 ↗ NCT02285699 ↗ NCT00048815 ↗ NCT00993876 ↗ NCT06796946 ↗ NCT00666757 ↗ NCT00609531 ↗ NCT01778686 ↗ NCT01153165 ↗ NCT00221494 ↗ NCT00108563 ↗ NCT00613470 ↗ NCT01575158 ↗ NCT01424384 ↗ NCT06412315 ↗ NCT00962039 ↗ NCT00977353 ↗ NCT00376051 ↗ NCT05588102 ↗ NCT00774813 ↗ NCT00939835 ↗ NCT00433121 ↗ NCT00676039 ↗ NCT03907215 ↗ NCT00893256 ↗ NCT00940238 ↗ NCT00208572 ↗ NCT01032083 ↗ NCT02022709 ↗ NCT00594269 ↗ NCT04846829 ↗ NCT01300364 ↗ NCT05271084 ↗ NCT01109030 ↗ NCT00538889 ↗ NCT01179568 ↗ NCT05957094 ↗ NCT02113943 ↗ NCT02000726 ↗ NCT06212284 ↗ NCT00226694 ↗ NCT01657760 ↗ NCT00351910 ↗ NCT00073658 ↗ NCT02825342 ↗ NCT01154647 ↗ NCT01099592 ↗ NCT01951053 ↗ NCT00865943 ↗ NCT04766229 ↗ NCT01716221 ↗ NCT00021528 ↗ NCT00254020 ↗ NCT00254007 ↗ NCT00692445 ↗ NCT05346445 ↗ NCT00477165 ↗ NCT04777838 ↗ NCT00680602 ↗ NCT01658228 ↗ NCT00602290 ↗ NCT00672659 ↗ NCT04497168 ↗ NCT00047671 ↗ NCT05063604 ↗ NCT03282110 ↗ NCT03499171 ↗ NCT02655354 ↗ NCT00162916 ↗ NCT02711215 ↗ NCT00297505 ↗ NCT00018902 ↗ NCT00317746 ↗ NCT01535573 ↗ NCT00794040 ↗ NCT00047450 ↗ NCT00067301 ↗ NCT06017037 ↗ NCT01436643 ↗ NCT00898807 ↗ NCT01254305 ↗ NCT02179268 ↗ NCT03607331 ↗ NCT04355455 ↗ NCT03746691 ↗ NCT01189812 ↗ NCT01978782 ↗ NCT01312922 ↗ NCT00249405 ↗ NCT03899285 ↗ NCT05735756 ↗ NCT02092974 ↗ NCT01032018 ↗ NCT01725048 ↗ NCT01557946 ↗ NCT04776226 ↗ NCT00834834 ↗ NCT00532519 ↗ NCT04169230 ↗ NCT00955474 ↗ NCT04590612 ↗ NCT00864890 ↗ NCT06025474 ↗ NCT00249886 ↗ NCT01667744 ↗ NCT02028026 ↗ NCT01041274 ↗ NCT06949644 ↗ NCT00896441 ↗ NCT00080158 ↗ NCT05041582 ↗ NCT04975724 ↗ NCT04097288 ↗ NCT01367756 ↗ NCT00269334 ↗ NCT04476030 ↗ NCT06192589 ↗ NCT01946607 ↗ NCT02080832 ↗ NCT00009204 ↗ NCT00865085 ↗ NCT00825825 ↗ NCT00217828 ↗ NCT01742832 ↗ NCT04145076 ↗ NCT01216449 ↗ NCT03516604 ↗ NCT00218036 ↗ NCT00838305 ↗ NCT01764867 ↗ NCT01937182 ↗ NCT02473250 ↗ NCT03854578 ↗ NCT00015548 ↗ NCT00044798 ↗ NCT01896349 ↗ NCT05627154 ↗ NCT01919216 ↗ NCT02386475 ↗ NCT02269540 ↗
Known as	Celexa	“Participants receive only clinical routine antidepressant treatment,Which include fluoxetine (Prozac); sertraline (Zoloft); paroxetine (Paxil); citalopram (Celexa)...” NCT01831440 ↗ 16 “Antidepressant medications may include the following: citalopram (Celexa), escitalopram (Lexapro), paroxetine (Paxil CR), sertraline (Zoloft), venlafaxine XR (Effexor XR),...” NCT00564278 ↗ “This study will evaluate the effectiveness of the stimulant medication methylphenidate (MPH, more commonly known as Ritalin ) when combined (or not combined) with the...” NCT00794040 ↗ “Throughout the study, all subjects will receive either escitalopram (Lexapro) or citalopram (Celexa) on the basis of the study doctor's clinical judgment.” NCT00361218 ↗ “METHOD: Effexor XR/Novo-venlafaxine XR 75 mg and Celexa/Gen-citalopram 40 mg were studied in a randomized crossover design.” PMID 19653973 ↗ Jul 2009 “This study will compare the safety and effectiveness two medications, citalopram (Celexa®) and risperidone (Risperdal®).” NCT00073658 ↗ “We will administer MDMA alone and in combination with the antidepressant citalopram (one trade name for this is Celexa).” NCT00838305 ↗ “antidepressant therapy with Celexa (Citalopram) in people suffering from Major Depressive Disorder.” NCT00067301 ↗ “Participants receive citalopram (Celexa) for 8 weeks and a placebo for 1 week.” NCT00047671 ↗ “Participants will take citalopram (Celexa)” NCT00047450 ↗ “citalopram hydrobromide (Celexa®) tablets” NCT03538691 ↗ “citalopram (Celexa and others)” NCT01944657 ↗ “Citalopram (Celexa)10-60;” NCT00074815 ↗ “Citalopram [Celexa]” NCT00009204 ↗ “citalopram (celexa)” NCT00254007 ↗ “citalopram_Celexa” NCT00817011 ↗ NCT02178696 ↗
Known as	CelexaTM	“CelexaTM 40 mg tablets, single dose” NCT00865085 ↗
Known as	cipralex	“citalopram (cipralex)” NCT00532519 ↗
Known as	Cipramil	“50 patients with reflux hypersensitivity and 50 patients with functional heartburn will receive either placebo or citalopram (Cipramil®) 20 mg as an add-on for a period of 8 weeks.” NCT03499171 ↗
Known as	CIT	“OBJECTIVE: To confirm the efficacy of a targeted complicated grief treatment (CGT), determine whether citalopram (CIT) enhances CGT outcome, and examine CIT efficacy without CGT.” PMID 27276373 ↗ Jul 2016 1 “Pipamperone/Citalopram (PNB01) Versus Citalopram (CIT) and Versus Pipamperone (PIP) in Major Depressive Disorder (MDD)” NCT01312922 ↗
Known as	Citalopram Aurobindo	“The medicinal product Citalopram Aurobindo contains citalopram as active ingredient available on the market in 20 mg film coated tablets. The tablets are divisible in two equal...” NCT04975724 ↗
Known as	Citalopram HBr	“Citalopram HBr eq. 10 mg tablets, single dose” NCT00865943 ↗ 2 “Citalopram HBr 40 mg tablets, single dose” NCT00865085 ↗ “Citalopram HBr 40 mg tablets, single dose” NCT00864890 ↗
Known as	Citalopram hydrobromide	“Citalopram Hydrobromide Tablets 40 mg: Test Product: Citalopram Hydrobromide Tablets 40 mg manufactured by Torrent Pharmaceuticals Limited, India” NCT00940238 ↗ 5 “the control group was given citalopram hydrobromide combined with zolpidem” NCT06740188 ↗ “citalopram hydrobromide (Celexa®) tablets” NCT03538691 ↗ NCT00086645 ↗ NCT00930293 ↗ NCT00363909 ↗
Known as	Citalopram, Celexa	“citalopram (Celexa)” NCT01460212 ↗ 1 “Citalopram, Celexa” NCT01916824 ↗
Known as	CTP	“OBJECTIVE: Despite the clinical importance of chronic and severe irritability, there is a paucity of controlled trials for its pharmacological treatment. Here, we examine the...” PMID 31128268 ↗ May 2019
Known as	Gen-Citalopram	“METHOD: Effexor XR/Novo-venlafaxine XR 75 mg and Celexa/Gen-citalopram 40 mg were studied in a randomized crossover design.” PMID 19653973 ↗ Jul 2009
Known as	seropram	ClinicalTrials.gov intervention name — accepted as the source's own label NCT07047651 ↗
Action	Inhibit	“citalopram, a selective serotonin reuptake inhibitor (SSRI)” NCT00217828 ↗
Modality	Small molecule	“citalopram, another SSRI” NCT00834834 ↗
Route	Oral	“taken orally” NCT00048815 ↗