drugset
drugset / Trial / NCT05271084

Pentoxifylline as an Adjunct to Citalopram in Adult Patients With Major Depressive Disorder

NCT05271084 ↗

Phase 1/2 Completed 100 enrolled Hawler Medical University
RandomizedParallel-groupDouble-blindTreatment

Summary

The aim of this study is to test if combining the antidepressant Citalopram with Pentoxifylline (PTX), a medicine with anti-inflammatory and phosphodiesterase inhibitory properties, enhanced antidepressant efficacy in adult patients with major depressive disorder (MDD) when compared to Citalopram alone.

Timeline

Start
2021-11-10
Primary completion
2022-02-25
Completion
2022-06-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Pentoxifylline Small molecule 400 mg —
Background Citalopram Small molecule 20 mg —

Indications

major depressive disorder