Combined Antidepressant and Behavioural Intervention

Summary

A body of evidence from both animal and human research suggests that antidepressant drugs may induce early changes in emotional processing that interact with environmental factors to produce a later change in mood. This experimental medicine study will examine the effect of citalopram on emotional cognition under different environmental conditions (as manipulated by the presence or absence of behavioural activation training). Participants will be administered either citalopram or placebo over the course of two weeks. Citalopram will be taken either alone or in combination with behavioural activation training.

Timeline

Start

2021-05-28

Primary completion

2023-11-17

Completion

2023-11-17

Drugs

Indications