drugset / Trial / NCT04590612

Improving Quality of Life in Early Parkinson's Disease

NCT04590612

Unknown 30 enrolled Western University, Canada
RandomizedParallel-groupDouble-blindTreatment

Summary

The study will examine 30 patients between ages 50-80, newly diagnosed with early-stage Parkinson's Disease. Patients will be randomized to receive either Citalopram or Carbidopa-levodopa. The investigators' primary outcome measure will be change in quality of life over a prospective period of 6 months. Secondary outcome measures will include change in mood state and motor symptoms, as well as comparison of improvement between two treatments. Primary investigators would also like to collect quantitative electroencephalogram (qEEG) recordings, which is a reading of brain activity as an additional interest of this study. Primary investigators will assess the qEEG recordings for electrophysiological findings before and after interventions.

Timeline

Start
2021-01
Primary completion
2022-01
Completion
2022-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Carbidopa Unknown 25 mg Oral
Subject Citalopram Small molecule 20 mg Oral
Comparator Levodopa Small molecule 100 mg Oral