drugset

drugset / Trial / NCT05618587

Effect of Lithium Therapy on Long COVID Symptoms

NCT05618587 ↗

Phase 2 Completed 52 enrolled State University of New York at Buffalo National Center for Advancing Translational Sciences (NCATS) · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study will assess low-dose lithium's effects on several different symptoms experienced by long COVID patients.

Timeline

Start: 2022-11-28
Primary completion: 2023-07-21
Completion: 2023-07-21

Outcome

Missed primary endpoint

registry analysis (superiority test); Lithium vs Placebo; p = 0.46; t-test, 2 sided NCT05618587 ↗

registry analysis (superiority test); Lithium vs Placebo; p = 0.79; t-test, 2 sided NCT05618587 ↗

Publications

Guttuso T Jr, Zhu J, Wilding GE. Lithium Aspartate for Long COVID Fatigue and Cognitive Dysfunction: A Randomized Clinical Trial. JAMA Netw Open. 2024 Oct 1;7(10):e2436874. doi: 10.1001/jamanetworkopen.2024.36874.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Lithium	Unknown	10 mg	Oral

Indications