drugset / Trial / NCT05638087

Dexamethasone Treatment for OSA in Children

NCT05638087 ↗

Phase 3 Completed 10 enrolled The Hospital for Sick Children
RandomizedParallel-groupTriple-blindTreatment

Summary

This is a double-blinded clinical trial of children diagnosed with moderate to severe obstructive sleep apnea (OSA) on a baseline polysomnogram (PSG). Participants will receive a 3-day course of dexamethasone, an oral steroid, or placebo control and undergo two PSGs to assess the efficacy of dexamethasone, as a treatment to manage the severity and symptoms in children with moderate to severe OSA.

Timeline

Start
2022-10-26
Primary completion
2024-07-21
Completion
2025-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule — Oral