drugset / Trial / NCT05642806
Comparison of Immune Profiles in Chronic Rhinosinusitis Patients After Mepolizumab Treatment
RandomizedParallel-groupTriple-blindTreatment
Summary
This study aims to analyze the immune profiles of patients with Chronic Rhinosinusitis with Nasal polyps (CRSwNP) with and without asthma before and after Mepolizumab. A group of participants with CRS without nasal polyps (CRSsNP) with asthma will be included to compare their immune profiles to CRSwNP.
Timeline
- Start
- 2023-07-01
- Primary completion
- 2024-12-30
- Completion
- 2025-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mepolizumab | Monoclonal antibody | 100 mg | Subcutaneous |