drugset
drugset / Trial / NCT05647993

Comparing of Cefazolin Plus Azithromycin Versus Cefazolin in Prevention of Febrile Morbidity After Emergency Cesarean Delivery

NCT05647993 ↗

Completed 172 enrolled Department of Medical Services Ministry of Public Health of Thailand
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Cesarean section is the common surgery in world wide. But the complication like febrile morbidity such as surgical site infection, fever, urinary tract infection and endometritis can be occurred even giving the standard antibiotics. Therefore if wider bacterial spectrum coverage antibiotic like azithromycin is added to the standard antimicrobial prophylaxis(1st generation cephalosporin), the incidence of febrile morbidity could be reduced. We will compare the regimen of cefazolin plus azithromycin and standard regimen of cefazolin alone in prevention of febrile morbidity after emergency cesarean section.

Timeline

Start
2022-12-14
Primary completion
2023-11-30
Completion
2023-12-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Azithromycin Small molecule 500 mg Intravenous
Background Cefazolin Small molecule 1 g Intravenous
Background Cefazolin Small molecule 2 g Intravenous
Background Cefazolin Small molecule 3 g Intravenous

Indications

No indication recorded.