Lepidium Sativum Extract Versus Simvastatin as an Adjunctive Local Delivery Agents to Non-Surgical Periodontal Therapy

Summary

The objectives of this clinical study were to: 1. Assess the influence of Lepidium sativum in situ gel versus simvastatin gel on the clinical parameters in periodontitis patients as the primary objective. 2. Detect the effect of locally delivered Lepidium sativum and simvastatin gels on the nuclear factor kappa B (NF-κB) level in gingival crevicular fluid as the secondary objective.

Timeline

Start

2021-09-01

Primary completion

2022-05-01

Completion

2022-07-01

Publications

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• Results 1.Abdelghany AM, El-Damrawi G, Oraby AH, Madshal MA. Optical and FTIR structural studies on CoO-doped strontium phosphate glasses. Journal of Non-Crystalline Solids. 2018 Nov 1;499:153-8.
• Results 2.Abdel-Hameed HS, El-Saeed SM, Ahmed NS, Nassar AM, El-Kafrawy AF, Hashem AI. Chemical transformation of Jojoba oil and Soybean oil and study of their uses as bio-lubricants. Industrial Crops and Products. 2022 Nov 1;187:115256.

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Indications