drugset / Trial / NCT05662813

Almonertinib Therapy in Patients With Abnormal Liver Function After EGFR-TKI Treatment, or Almonertinib First-line Therapy in Patients With Basic Hepatopathy

NCT05662813

Phase 2 Unknown 55 enrolled West China Hospital
NaSingle-groupOpen-labelTreatment

Summary

To assess the efficacy and safety of Almonertinib therapy in patients with abnormal liver function after first/second generation EGFR-TKI treatment, or Almonertinib first-line therapy in patients with basic hepatopathy and locally advanced or metastatic EGFR-mutant non-small cell lung cancer.

Timeline

Start
2022-11-09
Primary completion
2023-12-30
Completion
2025-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Almonertinib Small molecule 110 mg Oral