drugset / Trial / NCT05663801
Magnesium Sulphate Versus Ketamine as an Adjuvant to Bupivacaine in Pectoral Nerve Block During Mastectomy
RandomizedParallel-groupDouble-blindSupportive care
Summary
There are no published article that compare magnesium sulfate and ketamine as adjuvants to bupivacaine in PECS block , so the aim of this study is to evaluate the efficacy of Magnesium sulfate versus ketamine when added to local anesthetic ( Bupivacaine) in pectoral nerve block during mastectomy and detect which of these drugs has the more effective analgesic effect and decrease opioid consumption .
Timeline
- Start
- 2022-12-01
- Primary completion
- 2023-12-01
- Completion
- 2024-05-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ketamine | Small molecule | 0.25 % | Other |
| Comparator | Ketamine | Small molecule | 1 mg/kg | Other |
| Comparator | Ketamine | Small molecule | 30 ml | Other |
| Comparator | Magnesium Sulfate | Other / unclassified | 0.25 % | Other |
| Comparator | Magnesium Sulfate | Other / unclassified | 2 ml | Other |
| Comparator | Magnesium Sulfate | Other / unclassified | 28 ml | Other |
| Comparator | Magnesium Sulfate | Other / unclassified | 50 % | Other |
| Comparator | Bupivacaine | Other / unclassified | 0.25 % | Other |
| Comparator | Bupivacaine | Other / unclassified | 28 ml | Other |
| Comparator | Bupivacaine | Other / unclassified | 30 ml | Other |