drugset / Trial / NCT05673460

A Clinical Study of Nemtabrutinib in Japanese Participants With Hematological Malignancies (MK-1026-002)

NCT05673460

Phase 1 Completed 7 enrolled Merck Sharp & Dohme LLC
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study was to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of nemtabrutinib in Japanese participants with mature B-cell neoplasms.

Timeline

Start
2023-02-13
Primary completion
2025-04-28
Completion
2025-09-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Nemtabrutinib Other / unclassified 45 mg Oral
Subject Nemtabrutinib Other / unclassified 65 mg Oral