A Study of Brensocatib Following a Single Oral Administration in Participants With or Without Renal Impairment

Summary

The primary purpose of the study is to determine the pharmacokinetics (PK) following a single oral dose administration of brensocatib, safety, and tolerability of brensocatib when administered to participants with impaired renal function and in healthy participants.

Timeline

Start

2021-07-20

Primary completion

2023-02-14

Completion

2023-02-14

Publications

• Yeung SA, Stein DS, Marbury TC, Usansky H. The pharmacokinetics of brensocatib in participants with renal impairment following a single oral administration. Br J Clin Pharmacol. 2025 Apr;91(4):1191-1197. doi: 10.1111/bcp.16344. Epub 2024 Nov 22.

Drugs

Indications