drugset / Trial / NCT05675033

Serplulimab Combined With Anti-VEGF Antibody in Advanced Lung Adenocarcinoma

NCT05675033

Phase 2 Unknown 50 enrolled Fujian Cancer Hospital
NaSingle-groupOpen-labelTreatment

Summary

In order to further evaluate the efficacy of immunotherapy combined with antivascular therapy in the real world, we used Serpluimab combined with Bevacizumab and platinum-based chemotherapy in previously untreated EGFR/ALK-negative advanced non-squamous NSCLC patients, to evaluate the efficacy and safety of this regimen.

Timeline

Start
2023-01-10
Primary completion
2023-01-10
Completion
2024-01-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 7.5 mg/kg Intravenous
Subject Carboplatin Small molecule
Subject Pemetrexed Small molecule
Subject Serplulimab Monoclonal antibody 4.5 mg/kg Intravenous

Indications