Evaluation of Topical Encapsulated Benzoyl Peroxide on the Skin Microbiome and Skin Biophysical Properties

Summary

The overall objective of this study is to assess how the use of the drug may shift the skin microbiome and skin biophysical properties. Specifically, the study objectives were to assess the following: * How the drug affects the skin microbiome compared with vehicle when applied once daily for 8 weeks in subjects with papulopustular rosacea. * How the drug affects the skin physical properties compared with vehicle when applied once daily for 8 weeks in subjects with papulopustular rosacea.

Timeline

Start

2020-06-10

Primary completion

2021-07-15

Completion

2021-07-15

Publications

• Nong Y, Sugarman J, York JP, Levy-Hacham O, Nadora D, Mizrahi R, Galati A, Gallo RL, Sivamani RK. Effect of Topical Microencapsulated Benzoyl Peroxide on the Skin Microbiome in Rosacea: A Randomized, Double-Blind, Crossover, Vehicle-Controlled Clinical Trial. J Clin Aesthet Dermatol. 2024 Aug;17(8):19-26.

Drugs

Indications