drugset / Trial / NCT05689229

Aerosolized Versus Intravenous Colistin-based Antimicrobial Regimens in Hospitalized COVID-19 Patients With Bacterial Coinfection: A Randomized Controlled Trial

NCT05689229

Phase 3 Completed 128 enrolled Beni-Suef University
RandomizedParallel-groupOpen-labelTreatment

Summary

Secondary bacterial pathogen infection has been demonstrated to aggravate COVID-19 clinical outcomes. Bacterial infections acquired during a hospital stay are likely resistant to several antimicrobial medicines, making COVID-19 patient management difficult. As a result, it is believed that aerosolized colistin might be a viable choice for treating secondary bacterial infections caused by gram-negative resistant strains in individuals who also have COVID-19 infection.

Timeline

Start
2021-08-03
Primary completion
2021-11-28
Completion
2021-12-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Colistin Other / unclassified Intravenous