drugset / Trial / NCT05690698
Quetiapine Versus Haloperidol in the Management of Hyperactive Delirium
RandomizedParallel-groupDouble-blindTreatment
Summary
In population of intensive care unit (ICU), most studies compared atypical antipsychotics such as quetiapine with the traditional haloperidol in delirious patients of various forms and etiologies. The role of such agents in patients with hyperactive is not fully understood. This study compares the effectiveness of quetiapine with haloperidol in treating the hyperactive form of delirium in terms of their effects on morbidity, length of stay in the intensive care unit, and mortality in critically ill patients.
Timeline
- Start
- 2023-04-09
- Primary completion
- 2023-07-15
- Completion
- 2023-07-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Haloperidol | Other / unclassified | 1 mg | Oral |
| Comparator | Haloperidol | Other / unclassified | 2 mg | Oral |
| Subject | Quetiapine | Small molecule | 25 mg | — |
| Subject | Quetiapine | Small molecule | 50 mg | — |