drugset / Trial / NCT05699876

Melatonin vs Gabapentin for Post Trauma Surgery

NCT05699876

RandomizedParallel-groupSingle-blindTreatment

Summary

This project aims to compare the effect of preoperative administration of melatonin and gabapentin in reducing preoperative anxiety, stress markers and postoperative pain levels in trauma patients undergoing surgery. Gabapentin has analgesic as well as sedative properties. Melatonin, a hormone has been extensively used in intensive care units and has found to improve the sleep cycle and reduce pain. It is now being explored as a preoperative medication.

Timeline

Start
2023-01-15
Primary completion
2023-11-30
Completion
2023-11-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Gabapentin Small molecule
Subject Melatonin Small molecule 6 mg Oral

Indications