drugset / Trial / NCT05706636

T Central Memory Cells in Early Localized Non-Segmental Vitiligo

NCT05706636

Completed 22 enrolled Cairo University
RandomizedParallel-groupSingle-blindTreatment

Summary

Assessing the level of circulating TCMs (cluster of differentiation (CD) 8+, CD3+,C- chemokine receptor (CCR)7, cluster of differentiation 45 receptor (CD45R) cells) in early localized vitiligo cases prior to treatment and after treatment in comparison to healthy controls. This, in turn, would provide insights regarding the role of TCMs in vitiligo and the role of early treatment in halting disease progression and autoimmune memory formation that accounts for high recurrence rate of vitiligo

Timeline

Start
2023-02-01
Primary completion
2024-12-01
Completion
2025-04-15

Drugs

EvaluationDrugModalityDoseRoute
Comparator Dexamethasone Small molecule 5 mg Oral
Comparator Fluticasone Other / unclassified Topical
Comparator Tacrolimus Small molecule Topical

Indications