drugset / Trial / NCT05721027

Ibuprofen With or Without Dexamethasone for Acute Radicular Low Back Pain.

NCT05721027 ↗

Phase 4 Recruiting 132 enrolled Montefiore Medical Center
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This will be a placebo controlled, randomized, double-blind, comparative effectiveness study, in which we patients are enrolled during an emergency department (ED) visit for acute radicular low back pain (LBP) and followed by telephone two and seven days later. Patients will be randomized to receive an oral dose of dexamethasone for 2 consecutive days or placebo during an ED visit for acute radicular LBP. Every patient will receive a 7 day supply of ibuprofen and a low back pain education session.

Timeline

Start
2023-07-05
Primary completion
2027-10
Completion
2027-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 16 mg Oral
Background Ibuprofen Small molecule 400 mg Oral

Indications