drugset / Trial / NCT05723627

Comparison of Remimazolam and Propofol Effect on Oxygenation Reservoir During Diagnostic Gastric Endoscopy

NCT05723627

Completed 70 enrolled Yonsei University
RandomizedParallel-groupDouble-blindSupportive care

Summary

Propofol is one of the most commonly used sedative in endoscopic procedures, while its potency to induce respiratory depression may threaten patient safety. Remimazolam is known to less likely induce hemodynamic instability when compared to propofol, yet its favorable effects are not clearly evaluated in endoscopic procedures. Hence, this study aimed to compare hemodynamic effects of remimazolam and propofol, by evaluating oxygen reserve index (ORI) in patients scheduled for diagnostic gastric endoscopy.

Timeline

Start
2023-04-06
Primary completion
2023-09-21
Completion
2023-09-21

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Small molecule 0.5 mg/kg
Subject Remimazolam Small molecule 0.1 mg/kg

Indications

No indication recorded.