drugset / Trial / NCT05726175

Disitamab Vedotin(RC48) Combined With Penpulimab(AK105) for Neoadjuvant Treatment of HER2-low Breast Cancer

NCT05726175

Phase 2 Unknown 20 enrolled West China Hospital
NaSingle-groupOpen-labelTreatment

Summary

To evaluate the efficacy and safety of Disitamab Vedotin combined with Penpulimab as neoadjuvant therapy in patients with HER2-low early or locally advanced breast cancer

Timeline

Start
2023-03-01
Primary completion
2024-07-31
Completion
2024-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Disitamab Vedotin Monoclonal antibody 2 mg/kg Intravenous
Subject Penpulimab Monoclonal antibody 200 mg Intravenous

Indications