drugset / Trial / NCT05727891
Evaluation of Tonabersat for DME
Phase 2
Active not recruiting
128 enrolled
Jaeb Center for Health Research
Juvenile Diabetes Research Foundation · collabNational Eye Institute (NEI) · collabNational Institutes of Health (NIH) · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This randomized clinical trial will evaluate the effect of tonabersat compared with placebo on central subfield thickness (CST) in eyes with center-involved diabetic macular edema (CI-DME) and good visual acuity.
Timeline
- Start
- 2023-05-02
- Primary completion
- 2025-06-27
- Completion
- 2026-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Tonabersat | Small molecule | 80 mg | Oral |