drugset / Trial / NCT05733611

RP2/RP3 in Combination With Atezolizumab and Bevacizumab for the Treatment of Patients With CRC

NCT05733611 ↗

Phase 2 Terminated 5 enrolled Replimune, Inc. Roche Pharma AG · collab
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is an open-label, Phase 2 clinical trial evaluating therapy with an oncolytic immunotherapy (RP2 or RP3) in combination with atezolizumab and bevacizumab in patients with advanced Microsatellite Stable and Mismatch Repair Proficient Colorectal Carcinoma.

Timeline

Start
2023-06-29
Primary completion
2025-08-18
Completion
2025-08-18

Outcome

Outcome not reported

Stopped (Business): “Business reasons.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Atezolizumab Monoclonal antibody — —
Subject Bevacizumab Monoclonal antibody — —
Subject RP2 Other / unclassified — Other
Subject RP3 Unknown — Other

Indications