drugset / Trial / NCT05740969
Gene and Protein Expression Profiles After Treatment of Actinic Keratoses
RandomizedParallel-groupOpen-labelTreatment
Summary
The primary aim of this study is to investigate the effect of 5-fluorouracil, imiquimod, and melatonin for actinic keratosis on immunological gene, and protein expressions profiles. Secondarily, the aim is to assess the effect of the treatment on the histopathology of actinic keratoses.
Timeline
- Start
- 2023-02-01
- Primary completion
- 2024-02-01
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Imiquimod | Other / unclassified | 5 % | Topical |
| Subject | Melatonin | Small molecule | 2.5 % | Topical |
| Comparator | fluorouracil | Small molecule | 4 % | Topical |