Study to Assess Effect of Next-Generation Propellant MDI on Mucociliary Clearance Vs. HFA Propellant MDI in Healthy Participants

Summary

A Study to Assess the Effect of the HFO MDI Propellant on Mucociliary Clearance Compared to the HFA MDI Propellant in Healthy Participants

Timeline

Start

2023-06-14

Primary completion

2024-07-22

Completion

2024-07-22

Publications

• Donaldson SH, Zeman KL, Bell A, Jassal M, Pandya H, Bell JL, Puu M, Aurivillius M, Patel M, Bennett W. Mucociliary Clearance Following a Next-Generation Propellant Versus Hydrofluoroalkane-134a via Pressurized Metered-Dose Inhaler: A Randomized, Double-Blind, Two-Way Crossover Study in Healthy Adults. J Aerosol Med Pulm Drug Deliv. 2026 Jul 16:19412711261470884. doi: 10.1177/19412711261470884. Online ahead of print.

Drugs

Indications