Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Summary

This study will attempt to demonstrate the efficacy of Sodium Thiosulfate (STS) in preventing hearing loss in patients re-treated with cisplatin-based therapy according to regimens Cisplatin and STS (regimen CS) and Cisplatin, STS and Vorinostat/SAHA (regimen CSS).

Timeline

Start

2023-03-01

Primary completion

2027-01

Completion

2027-01

Outcome

Outcome not reported

Stopped: “This study will be closing at CCHMC and may be transferred to a principal investigator at another insitutiton.”

Drugs

Indications