Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Phase 0 Suspended 33 enrolled Children's Hospital Medical Center, Cincinnati

Non-randomizedParallel-groupOpen-labelSupportive care

Summary

This study will attempt to demonstrate the efficacy of Sodium Thiosulfate (STS) in preventing hearing loss in patients re-treated with cisplatin-based therapy according to regimens Cisplatin and STS (regimen CS) and Cisplatin, STS and Vorinostat/SAHA (regimen CSS).

Timeline

Start: 2023-03-01
Primary completion: 2027-01
Completion: 2027-01

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sodium Thiosulfate	Diagnostic / imaging agent	—	—

Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy

Summary

Timeline

Drugs

Indications