drugset / Trial / NCT05756907

Combination of SON-1010 (IL12-FHAB) and Atezolizumab in Patients With Platinum-resistant Ovarian Cancer

NCT05756907

Phase 1/2 Terminated 40 enrolled Sonnet BioTherapeutics Hoffmann-La Roche · collab
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a Phase 1b/2a, open-label, adaptive-design outpatient study to assess the safety, tolerability, and PK/PD of SON-1010 in combination with atezolizumab administered to patients with advanced solid tumors (Part 1) and patients with Platinum-resistant Ovarian Cancer (Part 2)

Timeline

Start
2023-09-15
Primary completion
2025-12-31
Completion
2026-01-08

Drugs

EvaluationDrugModalityDoseRoute
Subject SON-1010 Protein / enzyme biologic
Background Atezolizumab Monoclonal antibody

Indications