Effectiveness and Safety Study of Early add-on of Ezetimibe With Atorvastatin in Very High-risk Patients

Summary

This study aims to confirm the effectiveness of ezetimibe add-on therapy on LDL-C levels compared to atorvastatin monotherapy, especially in very high-risk patients. We intend to lay the foundation for a standard treatment for these patients through ezetimibe add on lipid-lowering therapy.

Timeline

Start

2023-07-26

Primary completion

2024-09-04

Completion

2024-10-15

Publications

• Kang SH, Kwon SU, Lee JY, Seo SM, Nam CW, Park GM, Hong YJ, Lee WY, Jang JE, Chae IH. The role of early ezetimibe combination with atorvastatin in patients with atherosclerotic cardiovascular disease. BMC Cardiovasc Disord. 2026 Feb 11;26(1):233. doi: 10.1186/s12872-026-05594-2.

Drugs

Indications